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Histone Demethylase LSD1 Inhibitors Prevent Cell Growth by Regulating Gene Expression in Esophageal Squamous Cell Carcinoma Cells.
Hoshino I, Akutsu Y, Murakami K, Akanuma N, Isozaki Y, Maruyama T, Toyozumi T, Matsumoto Y, Suito H, Takahashi M, Sekino N, Komatsu A, Suzuki T, Matsubara H. Hoshino I, et al. Among authors: takahashi m. Ann Surg Oncol. 2016 Jan;23(1):312-20. doi: 10.1245/s10434-015-4488-1. Epub 2015 Mar 20. Ann Surg Oncol. 2016. PMID: 25791791
Antitumor effects of metformin are a result of inhibiting nuclear factor kappa B nuclear translocation in esophageal squamous cell carcinoma.
Sekino N, Kano M, Matsumoto Y, Sakata H, Akutsu Y, Hanari N, Murakami K, Toyozumi T, Takahashi M, Otsuka R, Yokoyama M, Shiraishi T, Okada K, Hoshino I, Iida K, Akimoto AK, Matsubara H. Sekino N, et al. Among authors: takahashi m. Cancer Sci. 2018 Apr;109(4):1066-1074. doi: 10.1111/cas.13523. Epub 2018 Feb 26. Cancer Sci. 2018. PMID: 29396886 Free PMC article.
Genome-wide ChIP-seq data with a transcriptome analysis reveals the groups of genes regulated by histone demethylase LSD1 inhibition in esophageal squamous cell carcinoma cells.
Hoshino I, Takahashi M, Akutsu Y, Murakami K, Matsumoto Y, Suito H, Sekino N, Komatsu A, Iida K, Suzuki T, Inoue I, Ishige F, Iwatate Y, Matsubara H. Hoshino I, et al. Among authors: takahashi m. Oncol Lett. 2019 Jul;18(1):872-881. doi: 10.3892/ol.2019.10350. Epub 2019 May 13. Oncol Lett. 2019. PMID: 31289565 Free PMC article.
Metformin-Induced Heat Shock Protein Family A Member 6 Is a Promising Biomarker of Esophageal Squamous Cell Carcinoma.
Sekino N, Kano M, Kobayashi S, Murakami K, Sakata H, Toyozumi T, Endo S, Matsumoto Y, Suito H, Takahashi M, Otsuka R, Yokoyama M, Shiraishi T, Okada K, Kamata T, Ryuzaki T, Hirasawa S, Kinoshita K, Sasaki T, Iida K, Komatsu A, Matsubara H. Sekino N, et al. Among authors: takahashi m. Oncology. 2022;100(5):267-277. doi: 10.1159/000522446. Epub 2022 Feb 8. Oncology. 2022. PMID: 35134807
HIF-1α stimulates the progression of oesophageal squamous cell carcinoma by activating the Wnt/β-catenin signalling pathway.
Tang K, Toyozumi T, Murakami K, Sakata H, Kano M, Endo S, Matsumoto Y, Suito H, Takahashi M, Sekino N, Otsuka R, Kinoshita K, Hirasawa S, Hu J, Uesato M, Hayano K, Matsubara H. Tang K, et al. Among authors: takahashi m. Br J Cancer. 2022 Aug;127(3):474-487. doi: 10.1038/s41416-022-01825-3. Epub 2022 Apr 28. Br J Cancer. 2022. PMID: 35484214 Free PMC article.
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