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Fluorescence resonance energy transfer (FRET) and proximity ligation assays reveal functionally relevant homo- and heteromeric complexes among hyaluronan synthases HAS1, HAS2, and HAS3.
Bart G, Vico NO, Hassinen A, Pujol FM, Deen AJ, Ruusala A, Tammi RH, Squire A, Heldin P, Kellokumpu S, Tammi MI. Bart G, et al. Among authors: kellokumpu s. J Biol Chem. 2015 May 1;290(18):11479-90. doi: 10.1074/jbc.M115.640581. Epub 2015 Mar 20. J Biol Chem. 2015. PMID: 25795779 Free PMC article.
UDP-sugar substrates of HAS3 regulate its O-GlcNAcylation, intracellular traffic, extracellular shedding and correlate with melanoma progression.
Deen AJ, Arasu UT, Pasonen-Seppänen S, Hassinen A, Takabe P, Wojciechowski S, Kärnä R, Rilla K, Kellokumpu S, Tammi R, Tammi M, Oikari S. Deen AJ, et al. Among authors: kellokumpu s. Cell Mol Life Sci. 2016 Aug;73(16):3183-204. doi: 10.1007/s00018-016-2158-5. Epub 2016 Feb 16. Cell Mol Life Sci. 2016. PMID: 26883802 Free PMC article.
Dermatan sulfate epimerase 1 and dermatan 4-O-sulfotransferase 1 form complexes that generate long epimerized 4-O-sulfated blocks.
Tykesson E, Hassinen A, Zielinska K, Thelin MA, Frati G, Ellervik U, Westergren-Thorsson G, Malmström A, Kellokumpu S, Maccarana M. Tykesson E, et al. Among authors: kellokumpu s. J Biol Chem. 2018 Aug 31;293(35):13725-13735. doi: 10.1074/jbc.RA118.003875. Epub 2018 Jul 5. J Biol Chem. 2018. PMID: 29976758 Free PMC article.
Golgi pH, its regulation and roles in human disease.
Rivinoja A, Pujol FM, Hassinen A, Kellokumpu S. Rivinoja A, et al. Among authors: kellokumpu s. Ann Med. 2012 Sep;44(6):542-54. doi: 10.3109/07853890.2011.579150. Epub 2011 May 17. Ann Med. 2012. PMID: 21585247 Free article. Review.
The dimeric structure of wild-type human glycosyltransferase B4GalT1.
Harrus D, Khoder-Agha F, Peltoniemi M, Hassinen A, Ruddock L, Kellokumpu S, Glumoff T. Harrus D, et al. Among authors: kellokumpu s. PLoS One. 2018 Oct 23;13(10):e0205571. doi: 10.1371/journal.pone.0205571. eCollection 2018. PLoS One. 2018. PMID: 30352055 Free PMC article.
78 results