Zhang Y - Search Results

1

Non-canonical active site architecture of the radical SAM thiamin pyrimidine synthase.

Fenwick MK, Mehta AP, Zhang Y, Abdelwahed SH, Begley TP, Ealick SE. Fenwick MK, et al. Among authors: zhang y. Nat Commun. 2015 Mar 27;6:6480. doi: 10.1038/ncomms7480. Nat Commun. 2015. PMID: 25813242 Free PMC article.

2

Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily.

Chatterjee A, Li Y, Zhang Y, Grove TL, Lee M, Krebs C, Booker SJ, Begley TP, Ealick SE. Chatterjee A, et al. Among authors: zhang y. Nat Chem Biol. 2008 Dec;4(12):758-65. doi: 10.1038/nchembio.121. Epub 2008 Oct 26. Nat Chem Biol. 2008. PMID: 18953358 Free PMC article.

3

Diphthamide biosynthesis requires an organic radical generated by an iron-sulphur enzyme.

Zhang Y, Zhu X, Torelli AT, Lee M, Dzikovski B, Koralewski RM, Wang E, Freed J, Krebs C, Ealick SE, Lin H. Zhang Y, et al. Nature. 2010 Jun 17;465(7300):891-6. doi: 10.1038/nature09138. Nature. 2010. PMID: 20559380 Free PMC article.

4

A missing enzyme in thiamin thiazole biosynthesis: identification of TenI as a thiazole tautomerase.

Hazra AB, Han Y, Chatterjee A, Zhang Y, Lai RY, Ealick SE, Begley TP. Hazra AB, et al. Among authors: zhang y. J Am Chem Soc. 2011 Jun 22;133(24):9311-9. doi: 10.1021/ja1110514. Epub 2011 May 26. J Am Chem Soc. 2011. PMID: 21534620 Free PMC article.

5

Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate.

Lai RY, Huang S, Fenwick MK, Hazra A, Zhang Y, Rajashankar K, Philmus B, Kinsland C, Sanders JM, Ealick SE, Begley TP. Lai RY, et al. Among authors: zhang y. J Am Chem Soc. 2012 Jun 6;134(22):9157-9. doi: 10.1021/ja302474a. Epub 2012 May 24. J Am Chem Soc. 2012. PMID: 22568620 Free PMC article.

6

Active-site models for complexes of quinolinate synthase with substrates and intermediates.

Soriano EV, Zhang Y, Colabroy KL, Sanders JM, Settembre EC, Dorrestein PC, Begley TP, Ealick SE. Soriano EV, et al. Among authors: zhang y. Acta Crystallogr D Biol Crystallogr. 2013 Sep;69(Pt 9):1685-96. doi: 10.1107/S090744491301247X. Epub 2013 Aug 15. Acta Crystallogr D Biol Crystallogr. 2013. PMID: 23999292 Free PMC article.

7

Structure of a Clostridium botulinum C143S thiaminase I/thiamin complex reveals active site architecture.

Sikowitz MD, Shome B, Zhang Y, Begley TP, Ealick SE. Sikowitz MD, et al. Among authors: zhang y. Biochemistry. 2013 Nov 5;52(44):7830-9. doi: 10.1021/bi400841g. Epub 2013 Oct 25. Biochemistry. 2013. PMID: 24079939 Free PMC article.

8

Anaerobic 5-Hydroxybenzimidazole Formation from Aminoimidazole Ribotide: An Unanticipated Intersection of Thiamin and Vitamin B₁₂ Biosynthesis.

Mehta AP, Abdelwahed SH, Fenwick MK, Hazra AB, Taga ME, Zhang Y, Ealick SE, Begley TP. Mehta AP, et al. Among authors: zhang y. J Am Chem Soc. 2015 Aug 26;137(33):10444-7. doi: 10.1021/jacs.5b03576. Epub 2015 Aug 13. J Am Chem Soc. 2015. PMID: 26237670 Free PMC article.

9

Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis.

Dong M, Kathiresan V, Fenwick MK, Torelli AT, Zhang Y, Caranto JD, Dzikovski B, Sharma A, Lancaster KM, Freed JH, Ealick SE, Hoffman BM, Lin H. Dong M, et al. Among authors: zhang y. Science. 2018 Mar 16;359(6381):1247-1250. doi: 10.1126/science.aao6595. Science. 2018. PMID: 29590073 Free PMC article.

10

Structure of Escherichia coli AMP nucleosidase reveals similarity to nucleoside phosphorylases.

Zhang Y, Cottet SE, Ealick SE. Zhang Y, et al. Structure. 2004 Aug;12(8):1383-94. doi: 10.1016/j.str.2004.05.015. Structure. 2004. PMID: 15296732 Free article.

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