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Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo.
Borkin D, He S, Miao H, Kempinska K, Pollock J, Chase J, Purohit T, Malik B, Zhao T, Wang J, Wen B, Zong H, Jones M, Danet-Desnoyers G, Guzman ML, Talpaz M, Bixby DL, Sun D, Hess JL, Muntean AG, Maillard I, Cierpicki T, Grembecka J. Borkin D, et al. Among authors: pollock j. Cancer Cell. 2015 Apr 13;27(4):589-602. doi: 10.1016/j.ccell.2015.02.016. Epub 2015 Mar 26. Cancer Cell. 2015. PMID: 25817203 Free PMC article.
Property Focused Structure-Based Optimization of Small Molecule Inhibitors of the Protein-Protein Interaction between Menin and Mixed Lineage Leukemia (MLL).
Borkin D, Pollock J, Kempinska K, Purohit T, Li X, Wen B, Zhao T, Miao H, Shukla S, He M, Sun D, Cierpicki T, Grembecka J. Borkin D, et al. Among authors: pollock j. J Med Chem. 2016 Feb 11;59(3):892-913. doi: 10.1021/acs.jmedchem.5b01305. Epub 2016 Jan 25. J Med Chem. 2016. PMID: 26744767 Free PMC article.
Complexity of Blocking Bivalent Protein-Protein Interactions: Development of a Highly Potent Inhibitor of the Menin-Mixed-Lineage Leukemia Interaction.
Borkin D, Klossowski S, Pollock J, Miao H, Linhares BM, Kempinska K, Jin Z, Purohit T, Wen B, He M, Sun D, Cierpicki T, Grembecka J. Borkin D, et al. Among authors: pollock j. J Med Chem. 2018 Jun 14;61(11):4832-4850. doi: 10.1021/acs.jmedchem.8b00071. Epub 2018 May 23. J Med Chem. 2018. PMID: 29738674 Free PMC article.
High-Risk Melanoma: Stage Before Operating.
Makaranka S, Oo Z, Pollock J. Makaranka S, et al. Among authors: pollock j. Pigment Cell Melanoma Res. 2025 Jan;38(1):e13213. doi: 10.1111/pcmr.13213. Epub 2024 Dec 3. Pigment Cell Melanoma Res. 2025. PMID: 39625928
Using X-ray velocimetry to measure lung function and assess the efficacy of a pseudomonas aeruginosa bacteriophage therapy for cystic fibrosis.
Harker SA, Preissner M, Chang RY, Trevascus D, Liu C, Wang Y, Chow MYT, Cmielewski P, Reyne N, How YY, Pollock JA, Klein M, Wright CA, Dubsky S, Donnelley M, Chan HK, Morgan KS. Harker SA, et al. Among authors: pollock ja. Sci Rep. 2024 Nov 29;14(1):29727. doi: 10.1038/s41598-024-80326-0. Sci Rep. 2024. PMID: 39614107 Free PMC article.
1,348 results