Roy J - Search Results

1

DUPA conjugation of a cytotoxic indenoisoquinoline topoisomerase I inhibitor for selective prostate cancer cell targeting.

Roy J, Nguyen TX, Kanduluru AK, Venkatesh C, Lv W, Reddy PV, Low PS, Cushman M. Roy J, et al. J Med Chem. 2015 Apr 9;58(7):3094-103. doi: 10.1021/jm5018384. Epub 2015 Mar 30. J Med Chem. 2015. PMID: 25822623

2

Selective Tumor Targeting of Desacetyl Vinblastine Hydrazide and Tubulysin B via Conjugation to a Cholecystokinin 2 Receptor (CCK2R) Ligand.

Wayua C, Roy J, Putt KS, Low PS. Wayua C, et al. Among authors: roy j. Mol Pharm. 2015 Jul 6;12(7):2477-83. doi: 10.1021/acs.molpharmaceut.5b00218. Epub 2015 Jun 16. Mol Pharm. 2015. PMID: 26043355 Free PMC article.

3

Evaluation of a Carbonic Anhydrase IX-Targeted Near-Infrared Dye for Fluorescence-Guided Surgery of Hypoxic Tumors.

Lv PC, Roy J, Putt KS, Low PS. Lv PC, et al. Among authors: roy j. Mol Pharm. 2016 May 2;13(5):1618-25. doi: 10.1021/acs.molpharmaceut.6b00065. Epub 2016 Apr 4. Mol Pharm. 2016. PMID: 27043317 Free PMC article.

4

Evaluation of Nonpeptidic Ligand Conjugates for the Treatment of Hypoxic and Carbonic Anhydrase IX-Expressing Cancers.

Lv PC, Roy J, Putt KS, Low PS. Lv PC, et al. Among authors: roy j. Mol Cancer Ther. 2017 Mar;16(3):453-460. doi: 10.1158/1535-7163.MCT-16-0537. Epub 2016 Dec 15. Mol Cancer Ther. 2017. PMID: 27980101

5

Targeted Tubulysin B Hydrazide Conjugate for the Treatment of Luteinizing Hormone-Releasing Hormone Receptor-Positive Cancers.

Roy J, Kaake M, Srinivasarao M, Low PS. Roy J, et al. Bioconjug Chem. 2018 Jul 18;29(7):2208-2214. doi: 10.1021/acs.bioconjchem.8b00164. Epub 2018 Jun 13. Bioconjug Chem. 2018. PMID: 29851465

6

Small molecule targeted NIR dye conjugate for imaging LHRH receptor positive cancers.

Roy J, Kaake M, Low PS. Roy J, et al. Oncotarget. 2019 Jan 4;10(2):152-160. doi: 10.18632/oncotarget.26520. eCollection 2019 Jan 4. Oncotarget. 2019. PMID: 30719210 Free PMC article.

7

Design and validation of fibroblast activation protein alpha targeted imaging and therapeutic agents.

Roy J, Hettiarachchi SU, Kaake M, Mukkamala R, Low PS. Roy J, et al. Theranostics. 2020 Apr 27;10(13):5778-5789. doi: 10.7150/thno.41409. eCollection 2020. Theranostics. 2020. PMID: 32483418 Free PMC article.

8

Healing efficacy of fracture-targeted GSK3β inhibitor-loaded micelles for improved fracture repair.

Low SA, Galliford CV, Jones-Hall YL, Roy J, Yang J, Low PS, Kopeček J. Low SA, et al. Among authors: roy j. Nanomedicine (Lond). 2017 Feb;12(3):185-193. doi: 10.2217/nnm-2016-0340. Epub 2017 Jan 17. Nanomedicine (Lond). 2017. PMID: 28093944

9

Assessment of cholecystokinin 2 receptor (CCK2R) in neoplastic tissue.

Roy J, Putt KS, Coppola D, Leon ME, Khalil FK, Centeno BA, Clark N, Stark VE, Morse DL, Low PS. Roy J, et al. Oncotarget. 2016 Mar 22;7(12):14605-15. doi: 10.18632/oncotarget.7522. Oncotarget. 2016. PMID: 26910279 Free PMC article.

10

Targeted inhibition of PI3 kinase/mTOR specifically in fibrotic lung fibroblasts suppresses pulmonary fibrosis in experimental models.

Hettiarachchi SU, Li YH, Roy J, Zhang F, Puchulu-Campanella E, Lindeman SD, Srinivasarao M, Tsoyi K, Liang X, Ayaub EA, Nickerson-Nutter C, Rosas IO, Low PS. Hettiarachchi SU, et al. Among authors: roy j. Sci Transl Med. 2020 Oct 28;12(567):eaay3724. doi: 10.1126/scitranslmed.aay3724. Sci Transl Med. 2020. PMID: 33115948

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