Budha NR - Search Results

1

Modeling and Simulation to Support Phase 2 Dose Selection for RG7652, a Fully Human Monoclonal Antibody Against Proprotein Convertase Subtilisin/Kexin Type 9.

Budha NR, Leabman M, Jin JY, Wada DR, Baruch A, Peng K, Tingley WG, Davis JD. Budha NR, et al. AAPS J. 2015 Jul;17(4):881-90. doi: 10.1208/s12248-015-9750-8. Epub 2015 Mar 31. AAPS J. 2015. PMID: 25823668 Free PMC article. Clinical Trial.

2

Drug absorption interactions between oral targeted anticancer agents and PPIs: is pH-dependent solubility the Achilles heel of targeted therapy?

Budha NR, Frymoyer A, Smelick GS, Jin JY, Yago MR, Dresser MJ, Holden SN, Benet LZ, Ware JA. Budha NR, et al. Clin Pharmacol Ther. 2012 Aug;92(2):203-13. doi: 10.1038/clpt.2012.73. Epub 2012 Jun 27. Clin Pharmacol Ther. 2012. PMID: 22739140 Review.

3

A physiologically based pharmacokinetic (PBPK) approach to evaluate pharmacokinetics in patients with cancer.

Cheeti S, Budha NR, Rajan S, Dresser MJ, Jin JY. Cheeti S, et al. Among authors: budha nr. Biopharm Drug Dispos. 2013 Apr;34(3):141-54. doi: 10.1002/bdd.1830. Epub 2013 Feb 26. Biopharm Drug Dispos. 2013. PMID: 23225350

4

The use of betaine HCl to enhance dasatinib absorption in healthy volunteers with rabeprazole-induced hypochlorhydria.

Yago MR, Frymoyer A, Benet LZ, Smelick GS, Frassetto LA, Ding X, Dean B, Salphati L, Budha N, Jin JY, Dresser MJ, Ware JA. Yago MR, et al. AAPS J. 2014 Nov;16(6):1358-65. doi: 10.1208/s12248-014-9673-9. Epub 2014 Oct 2. AAPS J. 2014. PMID: 25274610 Free PMC article. Clinical Trial.

5

A Mechanistic Systems Pharmacology Model for Prediction of LDL Cholesterol Lowering by PCSK9 Antagonism in Human Dyslipidemic Populations.

Gadkar K, Budha N, Baruch A, Davis JD, Fielder P, Ramanujan S. Gadkar K, et al. CPT Pharmacometrics Syst Pharmacol. 2014 Nov 26;3(11):e149. doi: 10.1038/psp.2014.47. CPT Pharmacometrics Syst Pharmacol. 2014. PMID: 25426564 Free PMC article.

6

Critical role of bioanalytical strategies in investigation of clinical PK observations, a Phase I case study.

Peng K, Xu K, Liu L, Hendricks R, Delarosa R, Erickson R, Budha N, Leabman M, Song A, Kaur S, Fischer SK. Peng K, et al. MAbs. 2014;6(6):1500-8. doi: 10.4161/mabs.36208. MAbs. 2014. PMID: 25484037 Free PMC article. Clinical Trial.

7

Population pharmacokinetics and dosing implications for cobimetinib in patients with solid tumors.

Han K, Jin JY, Marchand M, Eppler S, Choong N, Hack SP, Tikoo N, Bruno R, Dresser M, Musib L, Budha NR. Han K, et al. Among authors: budha nr. Cancer Chemother Pharmacol. 2015 Nov;76(5):917-24. doi: 10.1007/s00280-015-2862-0. Epub 2015 Sep 13. Cancer Chemother Pharmacol. 2015. PMID: 26365290

8

Development of a Physiologically Based Pharmacokinetic Model for Itraconazole Pharmacokinetics and Drug-Drug Interaction Prediction.

Chen Y, Ma F, Lu T, Budha N, Jin JY, Kenny JR, Wong H, Hop CE, Mao J. Chen Y, et al. Clin Pharmacokinet. 2016 Jun;55(6):735-49. doi: 10.1007/s40262-015-0352-5. Clin Pharmacokinet. 2016. PMID: 26692192

9

Evaluation of Cytochrome P450 3A4-Mediated Drug-Drug Interaction Potential for Cobimetinib Using Physiologically Based Pharmacokinetic Modeling and Simulation.

Budha NR, Ji T, Musib L, Eppler S, Dresser M, Chen Y, Jin JY. Budha NR, et al. Clin Pharmacokinet. 2016 Nov;55(11):1435-1445. doi: 10.1007/s40262-016-0412-5. Clin Pharmacokinet. 2016. PMID: 27225997

10

Impact of physiologically based pharmacokinetic models on regulatory reviews and product labels: Frequent utilization in the field of oncology.

Yoshida K, Budha N, Jin JY. Yoshida K, et al. Clin Pharmacol Ther. 2017 May;101(5):597-602. doi: 10.1002/cpt.622. Epub 2017 Mar 15. Clin Pharmacol Ther. 2017. PMID: 28074611 Free PMC article. Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

38 results

Search Page

Filters