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Targeting the interleukin-11 receptor α in metastatic prostate cancer: A first-in-man study.
Pasqualini R, Millikan RE, Christianson DR, Cardó-Vila M, Driessen WH, Giordano RJ, Hajitou A, Hoang AG, Wen S, Barnhart KF, Baze WB, Marcott VD, Hawke DH, Do KA, Navone NM, Efstathiou E, Troncoso P, Lobb RR, Logothetis CJ, Arap W. Pasqualini R, et al. Among authors: driessen wh. Cancer. 2015 Jul 15;121(14):2411-21. doi: 10.1002/cncr.29344. Epub 2015 Apr 1. Cancer. 2015. PMID: 25832466 Free PMC article. Clinical Trial.
Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma.
Staquicini FI, Ozawa MG, Moya CA, Driessen WH, Barbu EM, Nishimori H, Soghomonyan S, Flores LG 2nd, Liang X, Paolillo V, Alauddin MM, Basilion JP, Furnari FB, Bogler O, Lang FF, Aldape KD, Fuller GN, Höök M, Gelovani JG, Sidman RL, Cavenee WK, Pasqualini R, Arap W. Staquicini FI, et al. Among authors: driessen wh. J Clin Invest. 2011 Jan;121(1):161-73. doi: 10.1172/JCI44798. Epub 2010 Dec 22. J Clin Invest. 2011. PMID: 21183793 Free PMC article.
A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys.
Barnhart KF, Christianson DR, Hanley PW, Driessen WH, Bernacky BJ, Baze WB, Wen S, Tian M, Ma J, Kolonin MG, Saha PK, Do KA, Hulvat JF, Gelovani JG, Chan L, Arap W, Pasqualini R. Barnhart KF, et al. Among authors: driessen wh. Sci Transl Med. 2011 Nov 9;3(108):108ra112. doi: 10.1126/scitranslmed.3002621. Sci Transl Med. 2011. PMID: 22072637 Free PMC article.
Selection and identification of ligand peptides targeting a model of castrate-resistant osteogenic prostate cancer and their receptors.
Mandelin J, Cardó-Vila M, Driessen WH, Mathew P, Navone NM, Lin SH, Logothetis CJ, Rietz AC, Dobroff AS, Proneth B, Sidman RL, Pasqualini R, Arap W. Mandelin J, et al. Among authors: driessen wh. Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3776-81. doi: 10.1073/pnas.1500128112. Epub 2015 Mar 11. Proc Natl Acad Sci U S A. 2015. PMID: 25762070 Free PMC article.
32 results