Singh SP - Search Results

1

Absorption and cleavage of enalapril, a carboxyl ester prodrug, in the rat intestine: in vitro, in situ intestinal perfusion and portal vein cannulation models.

Holenarsipur VK, Gaud N, Sinha J, Sivaprasad S, Bhutani P, Subramanian M, Singh SP, Arla R, Paruchury S, Sharma T, Marathe P, Mandlekar S. Holenarsipur VK, et al. Among authors: singh sp. Biopharm Drug Dispos. 2015 Sep;36(6):385-397. doi: 10.1002/bdd.1950. Epub 2015 May 4. Biopharm Drug Dispos. 2015. PMID: 25832562

2

Gender differences in pharmacokinetics of lumefantrine and its metabolite desbutyl-lumefantrine in rats.

Wahajuddin, Singh SP, Jain GK. Wahajuddin, et al. Among authors: singh sp. Biopharm Drug Dispos. 2012 May;33(4):229-34. doi: 10.1002/bdd.1786. Epub 2012 Apr 25. Biopharm Drug Dispos. 2012. PMID: 22447530

3

A simplified protocol employing elacridar in rodents: a screening model in drug discovery to assess P-gp mediated efflux at the blood brain barrier.

Kallem R, Kulkarni CP, Patel D, Thakur M, Sinz M, Singh SP, Mahammad SS, Mandlekar S. Kallem R, et al. Among authors: singh sp. Drug Metab Lett. 2012 Jun 1;6(2):134-44. Drug Metab Lett. 2012. PMID: 23061481

4

Prediction of human absorption of a trioxane antimalarial drug (CDRI 99/411) using an in-house validated in situ single-pass intestinal perfusion model.

Wahajuddin, Singh SP, Patel K, Pradhan T, Siddiqui HH, Singh SK. Wahajuddin, et al. Among authors: singh sp, singh sk. Arzneimittelforschung. 2011;61(9):532-7. doi: 10.1055/s-0031-1296240. Arzneimittelforschung. 2011. PMID: 22029231

5

Investigation of the functional role of P-glycoprotein in limiting the oral bioavailability of lumefantrine.

Wahajuddin, Raju KS, Singh SP, Taneja I. Wahajuddin, et al. Among authors: singh sp. Antimicrob Agents Chemother. 2014;58(1):489-94. doi: 10.1128/AAC.01382-13. Epub 2013 Nov 4. Antimicrob Agents Chemother. 2014. PMID: 24189249 Free PMC article.

6

Assessment of pharmacokinetic compatibility of short acting CDRI candidate trioxane derivative, 99-411, with long acting prescription antimalarials, lumefantrine and piperaquine.

Taneja I, Raju KS, Singh SP, Wahajuddin M. Taneja I, et al. Among authors: singh sp. Sci Rep. 2015 Nov 25;5:17264. doi: 10.1038/srep17264. Sci Rep. 2015. PMID: 26602250 Free PMC article.

7

Intravenous pharmacokinetics, oral bioavailability, dose proportionality and in situ permeability of anti-malarial lumefantrine in rats.

Wahajuddin, Singh SP, Raju KS, Nafis A, Puri SK, Jain GK. Wahajuddin, et al. Among authors: singh sp. Malar J. 2011 Oct 10;10:293. doi: 10.1186/1475-2875-10-293. Malar J. 2011. PMID: 21985153 Free PMC article.

8

Simultaneous determination of nine model compounds in permeability samples using RP-HPLC: application to prove the cassette administration principle in single pass intestinal perfusion study in rats.

Wahajuddin, Singh SP, Raju KS, Nafis A, Jain GK. Wahajuddin, et al. Among authors: singh sp. J Pharm Biomed Anal. 2012 Aug-Sep;67-68:71-6. doi: 10.1016/j.jpba.2012.03.048. Epub 2012 Apr 11. J Pharm Biomed Anal. 2012. PMID: 22613582

9

Development and validation of an LC-MS/MS method for simultaneous determination of piperaquine and 97-63, the active metabolite of CDRI 97-78, in rat plasma and its application in interaction study.

Wahajuddin M, Singh SP, Taneja I, Raju KS, Gayen JR, Siddiqui HH, Singh SK. Wahajuddin M, et al. Among authors: singh sp, singh sk. Drug Test Anal. 2016 Feb;8(2):221-7. doi: 10.1002/dta.1807. Epub 2015 May 14. Drug Test Anal. 2016. PMID: 25975936

10

In vivo prediction of CYP-mediated metabolic interaction potential of formononetin and biochanin A using in vitro human and rat CYP450 inhibition data.

Arora S, Taneja I, Challagundla M, Raju KS, Singh SP, Wahajuddin M. Arora S, et al. Among authors: singh sp. Toxicol Lett. 2015 Nov 19;239(1):1-8. doi: 10.1016/j.toxlet.2015.08.202. Epub 2015 Aug 13. Toxicol Lett. 2015. PMID: 26278343

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