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Tetrahydrobiopterin activates brown adipose tissue and regulates systemic energy metabolism.
Oguri Y, Fujita Y, Abudukadier A, Ohashi A, Goto T, Furuya F, Obara A, Fukushima T, Matsuo N, Kim M, Hosokawa M, Kawada T, Hasegawa H, Inagaki N. Oguri Y, et al. Among authors: abudukadier a. JCI Insight. 2017 May 4;2(9):e91981. doi: 10.1172/jci.insight.91981. eCollection 2017 May 4. JCI Insight. 2017. PMID: 28469071 Free PMC article.
Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes.
Perry RJ, Camporez JG, Kursawe R, Titchenell PM, Zhang D, Perry CJ, Jurczak MJ, Abudukadier A, Han MS, Zhang XM, Ruan HB, Yang X, Caprio S, Kaech SM, Sul HS, Birnbaum MJ, Davis RJ, Cline GW, Petersen KF, Shulman GI. Perry RJ, et al. Among authors: abudukadier a. Cell. 2015 Feb 12;160(4):745-758. doi: 10.1016/j.cell.2015.01.012. Epub 2015 Feb 5. Cell. 2015. PMID: 25662011 Free PMC article.
Second-generation antisense oligonucleotides against β-catenin protect mice against diet-induced hepatic steatosis and hepatic and peripheral insulin resistance.
Popov VB, Jornayvaz FR, Akgul EO, Kanda S, Jurczak MJ, Zhang D, Abudukadier A, Majumdar SK, Guigni B, Petersen KF, Manchem VP, Bhanot S, Shulman GI, Samuel VT. Popov VB, et al. Among authors: abudukadier a. FASEB J. 2016 Mar;30(3):1207-17. doi: 10.1096/fj.15-271999. Epub 2015 Dec 7. FASEB J. 2016. PMID: 26644352 Free PMC article.
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