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Therapeutic immunization with a mixture of herpes simplex virus 1 glycoprotein D-derived “asymptomatic” human CD8+ T-cell epitopes decreases spontaneous ocular shedding in latently infected HLA transgenic rabbits: association with low frequency of local PD-1+ TIM-3+ CD8+ exhausted T cells.
Khan AA, Srivastava R, Chentoufi AA, Geertsema R, Thai NT, Dasgupta G, Osorio N, Kalantari M, Nesburn AB, Wechsler SL, BenMohamed L. Khan AA, et al. Among authors: chentoufi aa. J Virol. 2015 Jul;89(13):6619-32. doi: 10.1128/JVI.00788-15. J Virol. 2015. PMID: 25878105 Free PMC article.
The herpes simplex virus 1 latency-associated transcript promotes functional exhaustion of virus-specific CD8+ T cells in latently infected trigeminal ganglia: a novel immune evasion mechanism.
Chentoufi AA, Kritzer E, Tran MV, Dasgupta G, Lim CH, Yu DC, Afifi RE, Jiang X, Carpenter D, Osorio N, Hsiang C, Nesburn AB, Wechsler SL, BenMohamed L. Chentoufi AA, et al. J Virol. 2011 Sep;85(17):9127-38. doi: 10.1128/JVI.00587-11. Epub 2011 Jun 29. J Virol. 2011. PMID: 21715478 Free PMC article.
The Herpes Simplex Virus Latency-Associated Transcript Gene Is Associated with a Broader Repertoire of Virus-Specific Exhausted CD8+ T Cells Retained within the Trigeminal Ganglia of Latently Infected HLA Transgenic Rabbits.
Srivastava R, Dervillez X, Khan AA, Chentoufi AA, Chilukuri S, Shukr N, Fazli Y, Ong NN, Afifi RE, Osorio N, Geertsema R, Nesburn AB, Wechsler SL, BenMohamed L. Srivastava R, et al. Among authors: chentoufi aa. J Virol. 2016 Mar 28;90(8):3913-3928. doi: 10.1128/JVI.02450-15. Print 2016 Apr. J Virol. 2016. PMID: 26842468 Free PMC article.
Immunodominant "asymptomatic" herpes simplex virus 1 and 2 protein antigens identified by probing whole-ORFome microarrays with serum antibodies from seropositive asymptomatic versus symptomatic individuals.
Dasgupta G, Chentoufi AA, Kalantari M, Falatoonzadeh P, Chun S, Lim CH, Felgner PL, Davies DH, BenMohamed L. Dasgupta G, et al. Among authors: chentoufi aa. J Virol. 2012 Apr;86(8):4358-69. doi: 10.1128/JVI.07107-11. Epub 2012 Feb 8. J Virol. 2012. PMID: 22318137 Free PMC article.
Asymptomatic HLA-A*02:01-restricted epitopes from herpes simplex virus glycoprotein B preferentially recall polyfunctional CD8+ T cells from seropositive asymptomatic individuals and protect HLA transgenic mice against ocular herpes.
Dervillez X, Qureshi H, Chentoufi AA, Khan AA, Kritzer E, Yu DC, Diaz OR, Gottimukkala C, Kalantari M, Villacres MC, Scarfone VM, McKinney DM, Sidney J, Sette A, Nesburn AB, Wechsler SL, BenMohamed L. Dervillez X, et al. Among authors: chentoufi aa. J Immunol. 2013 Nov 15;191(10):5124-38. doi: 10.4049/jimmunol.1301415. Epub 2013 Oct 7. J Immunol. 2013. PMID: 24101547 Free PMC article.
55 results