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Page 1
Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach.
Chollet A, Mourey L, Lherbet C, Delbot A, Julien S, Baltas M, Bernadou J, Pratviel G, Maveyraud L, Bernardes-Génisson V. Chollet A, et al. Among authors: baltas m. J Struct Biol. 2015 Jun;190(3):328-37. doi: 10.1016/j.jsb.2015.04.008. Epub 2015 Apr 17. J Struct Biol. 2015. PMID: 25891098
Design, chemical synthesis of 3-(9H-fluoren-9-yl)pyrrolidine-2,5-dione derivatives and biological activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis.
Matviiuk T, Rodriguez F, Saffon N, Mallet-Ladeira S, Gorichko M, de Jesus Lopes Ribeiro AL, Pasca MR, Lherbet C, Voitenko Z, Baltas M. Matviiuk T, et al. Among authors: baltas m. Eur J Med Chem. 2013;70:37-48. doi: 10.1016/j.ejmech.2013.09.041. Epub 2013 Oct 2. Eur J Med Chem. 2013. PMID: 24140915
Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity.
Oliveira PFM, Guidetti B, Chamayou A, André-Barrès C, Madacki J, Korduláková J, Mori G, Orena BS, Chiarelli LR, Pasca MR, Lherbet C, Carayon C, Massou S, Baron M, Baltas M. Oliveira PFM, et al. Among authors: baltas m. Molecules. 2017 Sep 1;22(9):1457. doi: 10.3390/molecules22091457. Molecules. 2017. PMID: 28862683 Free PMC article.
62 results