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Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach.
Chollet A, Mourey L, Lherbet C, Delbot A, Julien S, Baltas M, Bernadou J, Pratviel G, Maveyraud L, Bernardes-Génisson V. Chollet A, et al. Among authors: bernadou j. J Struct Biol. 2015 Jun;190(3):328-37. doi: 10.1016/j.jsb.2015.04.008. Epub 2015 Apr 17. J Struct Biol. 2015. PMID: 25891098
Evaluation of the inhibitory activity of (aza)isoindolinone-type compounds: toward in vitro InhA action, Mycobacterium tuberculosis growth and mycolic acid biosynthesis.
Chollet A, Stigliani JL, Pasca MR, Mori G, Lherbet C, Constant P, Quémard A, Bernadou J, Pratviel G, Bernardes-Génisson V. Chollet A, et al. Among authors: bernadou j. Chem Biol Drug Des. 2016 Nov;88(5):740-755. doi: 10.1111/cbdd.12804. Epub 2016 Jul 16. Chem Biol Drug Des. 2016. PMID: 27301022
85 results