Bruckmueller H - Search Results

1

Phenotype-Genotype Correlation Applying a Cocktail Approach and an Exome Chip Analysis Reveals Further Variants Contributing to Variation of Drug Metabolism.

Böhm R, Bruckmueller H, Oswald S, Hübenthal M, Kaehler M, Ehmke L, Höcker J, Siegmund W, Franke A, Cascorbi I. Böhm R, et al. Among authors: bruckmueller h. Clin Pharmacol Ther. 2024 Jul;116(1):204-216. doi: 10.1002/cpt.3270. Epub 2024 Apr 18. Clin Pharmacol Ther. 2024. PMID: 38637968

2

Genome‑wide expression and methylation analyses reveal aberrant cell adhesion signaling in tyrosine kinase inhibitor‑resistant CML cells.

Kaehler M, Litterst M, Kolarova J, Böhm R, Bruckmueller H, Ammerpohl O, Cascorbi I, Nagel I. Kaehler M, et al. Among authors: bruckmueller h. Oncol Rep. 2022 Aug;48(2):144. doi: 10.3892/or.2022.8355. Epub 2022 Jun 22. Oncol Rep. 2022. PMID: 35730629 Free PMC article.

3

Drug-Drug-Gene Interactions: A Call for Clinical Consideration.

Bruckmueller H, Cascorbi I. Bruckmueller H, et al. Clin Pharmacol Ther. 2021 Sep;110(3):549-551. doi: 10.1002/cpt.2348. Epub 2021 Jul 18. Clin Pharmacol Ther. 2021. PMID: 34278570 No abstract available.

4

Interaction of Phytocompounds of Echinacea purpurea with ABCB1 and ABCG2 Efflux Transporters.

Awortwe C, Bruckmueller H, Kaehler M, Cascorbi I. Awortwe C, et al. Among authors: bruckmueller h. Mol Pharm. 2021 Apr 5;18(4):1622-1633. doi: 10.1021/acs.molpharmaceut.0c01075. Epub 2021 Mar 17. Mol Pharm. 2021. PMID: 33730506

5

ABCB1, ABCG2, ABCC1, ABCC2, and ABCC3 drug transporter polymorphisms and their impact on drug bioavailability: what is our current understanding?

Bruckmueller H, Cascorbi I. Bruckmueller H, et al. Expert Opin Drug Metab Toxicol. 2021 Apr;17(4):369-396. doi: 10.1080/17425255.2021.1876661. Epub 2021 Feb 2. Expert Opin Drug Metab Toxicol. 2021. PMID: 33459081 Review.

6

The serotonin receptor 2A (HTR2A) rs6313 variant is associated with higher ongoing pain and signs of central sensitization in neuropathic pain patients.

Sachau J, Bruckmueller H, Gierthmühlen J, Magerl W, May D, Binder A, Forstenpointner J, Koetting J, Maier C, Tölle TR, Treede RD, Berthele A, Caliebe A, Diesch C, Flor H, Huge V, Maihöfner C, Rehm S, Kersebaum D, Fabig SC, Vollert J, Rolke R, Stemmler S, Sommer C, Westermann A, Cascorbi I, Baron R. Sachau J, et al. Among authors: bruckmueller h. Eur J Pain. 2021 Mar;25(3):595-611. doi: 10.1002/ejp.1696. Epub 2020 Dec 3. Eur J Pain. 2021. PMID: 33171011

7

Expression differences of miR-142-5p between treatment-naïve chronic myeloid leukemia patients responding and non-responding to imatinib therapy suggest a link to oncogenic ABL2, SRI, cKIT and MCL1 signaling pathways critical for development of therapy resistance.

Klümper T, Bruckmueller H, Diewock T, Kaehler M, Haenisch S, Pott C, Bruhn O, Cascorbi I. Klümper T, et al. Among authors: bruckmueller h. Exp Hematol Oncol. 2020 Sep 26;9:26. doi: 10.1186/s40164-020-00183-1. eCollection 2020. Exp Hematol Oncol. 2020. PMID: 32999756 Free PMC article.

8

Phosphorylation of steroid receptor coactivator-3 (SRC-3) at serine 857 is regulated by the p38^MAPK-MK2 axis and affects NF-κB-mediated transcription.

Shrestha A, Bruckmueller H, Kildalsen H, Kaur G, Gaestel M, Wetting HL, Mikkola I, Seternes OM. Shrestha A, et al. Among authors: bruckmueller h. Sci Rep. 2020 Jul 9;10(1):11388. doi: 10.1038/s41598-020-68219-4. Sci Rep. 2020. PMID: 32647362 Free PMC article.

9

Transcriptional and Post-Transcriptional Regulation of Duodenal P-Glycoprotein and MRP2 in Healthy Human Subjects after Chronic Treatment with Rifampin and Carbamazepine.

Brueck S, Bruckmueller H, Wegner D, Busch D, Martin P, Oswald S, Cascorbi I, Siegmund W. Brueck S, et al. Among authors: bruckmueller h. Mol Pharm. 2019 Sep 3;16(9):3823-3830. doi: 10.1021/acs.molpharmaceut.9b00458. Epub 2019 Aug 9. Mol Pharm. 2019. PMID: 31361500

10

Implications of genetic variation of common Drug Metabolizing Enzymes and ABC Transporters among the Pakistani Population.

Afsar NA, Bruckmueller H, Werk AN, Nisar MK, Ahmad HR, Cascorbi I. Afsar NA, et al. Among authors: bruckmueller h. Sci Rep. 2019 May 13;9(1):7323. doi: 10.1038/s41598-019-43736-z. Sci Rep. 2019. PMID: 31086207 Free PMC article.

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