Hershfield JR - Search Results

1

Origins of Yersinia pestis sensitivity to the arylomycin antibiotics and the inhibition of type I signal peptidase.

Steed DB, Liu J, Wasbrough E, Miller L, Halasohoris S, Miller J, Somerville B, Hershfield JR, Romesberg FE. Steed DB, et al. Among authors: hershfield jr. Antimicrob Agents Chemother. 2015 Jul;59(7):3887-98. doi: 10.1128/AAC.00181-15. Epub 2015 Apr 20. Antimicrob Agents Chemother. 2015. PMID: 25896690 Free PMC article.

2

In vitro antibiotic susceptibilities of Yersinia pestis determined by broth microdilution following CLSI methods.

Heine HS, Hershfield J, Marchand C, Miller L, Halasohoris S, Purcell BK, Worsham PL. Heine HS, et al. Antimicrob Agents Chemother. 2015 Apr;59(4):1919-21. doi: 10.1128/AAC.04548-14. Epub 2015 Jan 12. Antimicrob Agents Chemother. 2015. PMID: 25583720 Free PMC article.

3

In Vitro and In Vivo Activity of Omadacycline against Two Biothreat Pathogens, Bacillus anthracis and Yersinia pestis.

Steenbergen J, Tanaka SK, Miller LL, Halasohoris SA, Hershfield JR. Steenbergen J, et al. Among authors: hershfield jr. Antimicrob Agents Chemother. 2017 Apr 24;61(5):e02434-16. doi: 10.1128/AAC.02434-16. Print 2017 May. Antimicrob Agents Chemother. 2017. PMID: 28223382 Free PMC article.

4

Efficacy of Intravenously Administered Gepotidacin in Cynomolgus Macaques following a Francisella tularensis Inhalational Challenge.

Jakielaszek C, Hilliard JJ, Mannino F, Hossain M, Qian L, Fishman C, Chou YL, Henning L, Novak J, Demons S, Hershfield J, O'Dwyer K. Jakielaszek C, et al. Antimicrob Agents Chemother. 2023 May 17;67(5):e0138122. doi: 10.1128/aac.01381-22. Epub 2023 Apr 25. Antimicrob Agents Chemother. 2023. PMID: 37097147 Free PMC article.

5

Efficacy of therapeutically administered gepotidacin in a rabbit model of inhalational anthrax.

Hilliard JJ, Jakielaszek C, Mannino F, Hossain M, Qian L, Fishman C, Demons S, Hershfield J, Soffler C, Russo R, Henning L, Novak J, O'Dwyer K. Hilliard JJ, et al. Antimicrob Agents Chemother. 2024 Mar 6;68(3):e0149723. doi: 10.1128/aac.01497-23. Epub 2024 Feb 15. Antimicrob Agents Chemother. 2024. PMID: 38358266 Free PMC article.

6

3-substituted indole inhibitors against Francisella tularensis FabI identified by structure-based virtual screening.

Hu X, Compton JR, Abdulhameed MD, Marchand CL, Robertson KL, Leary DH, Jadhav A, Hershfield JR, Wallqvist A, Friedlander AM, Legler PM. Hu X, et al. Among authors: hershfield jr. J Med Chem. 2013 Jul 11;56(13):5275-87. doi: 10.1021/jm4001242. Epub 2013 Jul 1. J Med Chem. 2013. PMID: 23815100

7

Gepotidacin is efficacious in a nonhuman primate model of pneumonic plague.

Jakielaszek C, Hossain M, Qian L, Fishman C, Widdowson K, Hilliard JJ, Mannino F, Raychaudhuri A, Carniel E, Demons S, Heine HS, Hershfield J, Russo R, Mega WM, Revelli D, O'Dwyer K. Jakielaszek C, et al. Sci Transl Med. 2022 Jun;14(647):eabg1787. doi: 10.1126/scitranslmed.abg1787. Epub 2022 Jun 1. Sci Transl Med. 2022. PMID: 35648812

8

Plantazolicin is an ultra-narrow spectrum antibiotic that targets the Bacillus anthracis membrane.

Molohon KJ, Saint-Vincent PMB, Park S, Doroghazi JR, Maxson T, Hershfield JR, Flatt KM, Schroeder NE, Ha T, Mitchell DA. Molohon KJ, et al. Among authors: hershfield jr. ACS Infect Dis. 2016 Mar 10;2(3):207-220. doi: 10.1021/acsinfecdis.5b00115. Epub 2015 Dec 23. ACS Infect Dis. 2016. PMID: 27152321 Free PMC article.

9

Membrane-Targeting DCAP Analogues with Broad-Spectrum Antibiotic Activity against Pathogenic Bacteria.

Hurley KA, Heinrich VA, Hershfield JR, Demons ST, Weibel DB. Hurley KA, et al. Among authors: hershfield jr. ACS Med Chem Lett. 2015 Mar 1;6(4):466-71. doi: 10.1021/acsmedchemlett.5b00024. eCollection 2015 Apr 9. ACS Med Chem Lett. 2015. PMID: 25941556 Free PMC article.

10

A Review of Force Health Protection Aspects of Lyme Disease in the U.S. Military.

Melanson VR, Bateman SL, Hering K, Weiss TJ, Reilly JL, Davis KT, Gramlich VA, Jankovich A, Daffin M, Hershfield JR, Barnhill JC. Melanson VR, et al. Among authors: hershfield jr. Mil Med. 2024 Sep 10:usae415. doi: 10.1093/milmed/usae415. Online ahead of print. Mil Med. 2024. PMID: 39255240

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