Mably AJ - Search Results

1

A human monoclonal IgG that binds aβ assemblies and diverse amyloids exhibits anti-amyloid activities in vitro and in vivo.

Levites Y, O'Nuallain B, Puligedda RD, Ondrejcak T, Adekar SP, Chen C, Cruz PE, Rosario AM, Macy S, Mably AJ, Walsh DM, Vidal R, Solomon A, Brown D, Rowan MJ, Golde TE, Dessain SK. Levites Y, et al. Among authors: mably aj. J Neurosci. 2015 Apr 22;35(16):6265-76. doi: 10.1523/JNEUROSCI.5109-14.2015. J Neurosci. 2015. PMID: 25904780 Free PMC article.

2

Peripheral administration of a humanized anti-PrP antibody blocks Alzheimer's disease Aβ synaptotoxicity.

Klyubin I, Nicoll AJ, Khalili-Shirazi A, Farmer M, Canning S, Mably A, Linehan J, Brown A, Wakeling M, Brandner S, Walsh DM, Rowan MJ, Collinge J. Klyubin I, et al. Among authors: mably a. J Neurosci. 2014 Apr 30;34(18):6140-5. doi: 10.1523/JNEUROSCI.3526-13.2014. J Neurosci. 2014. PMID: 24790184 Free PMC article.

3

Alzheimer's disease brain-derived amyloid-β-mediated inhibition of LTP in vivo is prevented by immunotargeting cellular prion protein.

Barry AE, Klyubin I, Mc Donald JM, Mably AJ, Farrell MA, Scott M, Walsh DM, Rowan MJ. Barry AE, et al. Among authors: mably aj. J Neurosci. 2011 May 18;31(20):7259-63. doi: 10.1523/JNEUROSCI.6500-10.2011. J Neurosci. 2011. PMID: 21593310 Free PMC article.

4

Human anti-Aβ IgGs target conformational epitopes on synthetic dimer assemblies and the AD brain-derived peptide.

Welzel AT, Williams AD, McWilliams-Koeppen HP, Acero L, Weber A, Blinder V, Mably A, Bunk S, Hermann C, Farrell MA, Ehrlich HJ, Schwarz HP, Walsh DM, Solomon A, O'Nuallain B. Welzel AT, et al. PLoS One. 2012;7(11):e50317. doi: 10.1371/journal.pone.0050317. Epub 2012 Nov 27. PLoS One. 2012. PMID: 23209707 Free PMC article.

5

Neurotransmitter receptor and time dependence of the synaptic plasticity disrupting actions of Alzheimer's disease Aβ in vivo.

Klyubin I, Ondrejcak T, Hayes J, Cullen WK, Mably AJ, Walsh DM, Rowan MJ. Klyubin I, et al. Among authors: mably aj. Philos Trans R Soc Lond B Biol Sci. 2013 Dec 2;369(1633):20130147. doi: 10.1098/rstb.2013.0147. Print 2014 Jan 5. Philos Trans R Soc Lond B Biol Sci. 2013. PMID: 24298149 Free PMC article.

6

mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo.

Hu NW, Nicoll AJ, Zhang D, Mably AJ, O'Malley T, Purro SA, Terry C, Collinge J, Walsh DM, Rowan MJ. Hu NW, et al. Among authors: mably aj. Nat Commun. 2014 Mar 4;5:3374. doi: 10.1038/ncomms4374. Nat Commun. 2014. PMID: 24594908 Free PMC article.

7

Anti-Aβ antibodies incapable of reducing cerebral Aβ oligomers fail to attenuate spatial reference memory deficits in J20 mice.

Mably AJ, Liu W, Mc Donald JM, Dodart JC, Bard F, Lemere CA, O'Nuallain B, Walsh DM. Mably AJ, et al. Neurobiol Dis. 2015 Oct;82:372-384. doi: 10.1016/j.nbd.2015.07.008. Epub 2015 Jul 26. Neurobiol Dis. 2015. PMID: 26215784 Free PMC article.

8

Peripheral Interventions Enhancing Brain Glutamate Homeostasis Relieve Amyloid β- and TNFα- Mediated Synaptic Plasticity Disruption in the Rat Hippocampus.

Zhang D, Mably AJ, Walsh DM, Rowan MJ. Zhang D, et al. Among authors: mably aj. Cereb Cortex. 2017 Jul 1;27(7):3724-3735. doi: 10.1093/cercor/bhw193. Cereb Cortex. 2017. PMID: 27390019 Free PMC article.

9

Cellular Prion Protein Mediates the Disruption of Hippocampal Synaptic Plasticity by Soluble Tau In Vivo.

Ondrejcak T, Klyubin I, Corbett GT, Fraser G, Hong W, Mably AJ, Gardener M, Hammersley J, Perkinton MS, Billinton A, Walsh DM, Rowan MJ. Ondrejcak T, et al. Among authors: mably aj. J Neurosci. 2018 Dec 12;38(50):10595-10606. doi: 10.1523/JNEUROSCI.1700-18.2018. Epub 2018 Oct 24. J Neurosci. 2018. PMID: 30355631 Free PMC article.

10

Alzheimer brain-derived amyloid β-protein impairs synaptic remodeling and memory consolidation.

Borlikova GG, Trejo M, Mably AJ, Mc Donald JM, Sala Frigerio C, Regan CM, Murphy KJ, Masliah E, Walsh DM. Borlikova GG, et al. Among authors: mably aj. Neurobiol Aging. 2013 May;34(5):1315-27. doi: 10.1016/j.neurobiolaging.2012.10.028. Epub 2012 Nov 22. Neurobiol Aging. 2013. PMID: 23182244 Free PMC article.

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