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Neutralizing antibodies elicited by a novel detoxified pneumolysin derivative, PlyD1, provide protection against both pneumococcal infection and lung injury.
Salha D, Szeto J, Myers L, Claus C, Sheung A, Tang M, Ljutic B, Hanwell D, Ogilvie K, Ming M, Messham B, van den Dobbelsteen G, Hopfer R, Ochs MM, Gallichan S. Salha D, et al. Among authors: gallichan s. Infect Immun. 2012 Jun;80(6):2212-20. doi: 10.1128/IAI.06348-11. Epub 2012 Apr 2. Infect Immun. 2012. PMID: 22473606 Free PMC article.
A bivalent pneumococcal histidine triad protein D-choline-binding protein A vaccine elicits functional antibodies that passively protect mice from Streptococcus pneumoniae challenge.
Ochs MM, Williams K, Sheung A, Lheritier P, Visan L, Rouleau N, Proust E, de Montfort A, Tang M, Mari K, Hopfer R, Gallichan S, Brookes RH. Ochs MM, et al. Among authors: gallichan s. Hum Vaccin Immunother. 2016 Nov;12(11):2946-2952. doi: 10.1080/21645515.2016.1202389. Hum Vaccin Immunother. 2016. PMID: 27392182 Free PMC article. Clinical Trial.
Protection of outbred mice against a vaginal challenge by a Chlamydia trachomatis serovar E recombinant major outer membrane protein vaccine is dependent on phosphate substitution in the adjuvant.
Pal S, Ausar SF, Tifrea DF, Cheng C, Gallichan S, Sanchez V, de la Maza LM, Visan L. Pal S, et al. Among authors: gallichan s. Hum Vaccin Immunother. 2020 Oct 2;16(10):2537-2547. doi: 10.1080/21645515.2020.1717183. Epub 2020 Mar 2. Hum Vaccin Immunother. 2020. PMID: 32118511 Free PMC article.
A respiratory syncytial virus (RSV) F protein nanoparticle vaccine focuses antibody responses to a conserved neutralization domain.
Swanson KA, Rainho-Tomko JN, Williams ZP, Lanza L, Peredelchuk M, Kishko M, Pavot V, Alamares-Sapuay J, Adhikarla H, Gupta S, Chivukula S, Gallichan S, Zhang L, Jackson N, Yoon H, Edwards D, Wei CJ, Nabel GJ. Swanson KA, et al. Among authors: gallichan s. Sci Immunol. 2020 May 1;5(47):eaba6466. doi: 10.1126/sciimmunol.aba6466. Sci Immunol. 2020. PMID: 32358170
Immunogenicity and protective efficacy of RSV G central conserved domain vaccine with a prefusion nanoparticle.
Rainho-Tomko JN, Pavot V, Kishko M, Swanson K, Edwards D, Yoon H, Lanza L, Alamares-Sapuay J, Osei-Bonsu R, Mundle ST, Murison DA, Gallichan S, Delagrave S, Wei CJ, Zhang L, Nabel GJ. Rainho-Tomko JN, et al. Among authors: gallichan s. NPJ Vaccines. 2022 Jun 30;7(1):74. doi: 10.1038/s41541-022-00487-9. NPJ Vaccines. 2022. PMID: 35773301 Free PMC article.
Burden of respiratory syncytial virus infection in community-dwelling older adults in Europe (RESCEU): an international prospective cohort study.
Korsten K, Adriaenssens N, Coenen S, Butler C, Ravanfar B, Rutter H, Allen J, Falsey A, Pirçon JY, Gruselle O, Pavot V, Vernhes C, Balla-Jhagjhoorsingh S, Öner D, Ispas G, Aerssens J, Shinde V, Verheij T, Bont L, Wildenbeest J; RESCEU investigators. Korsten K, et al. Eur Respir J. 2021 Apr 1;57(4):2002688. doi: 10.1183/13993003.02688-2020. Print 2021 Apr. Eur Respir J. 2021. PMID: 33060153 Free article.
Distinct patterns of within-host virus populations between two subgroups of human respiratory syncytial virus.
Lin GL, Drysdale SB, Snape MD, O'Connor D, Brown A, MacIntyre-Cockett G, Mellado-Gomez E, de Cesare M, Bonsall D, Ansari MA, Öner D, Aerssens J, Butler C, Bont L, Openshaw P, Martinón-Torres F, Nair H, Bowden R; RESCEU Investigators; Golubchik T, Pollard AJ. Lin GL, et al. Nat Commun. 2021 Aug 26;12(1):5125. doi: 10.1038/s41467-021-25265-4. Nat Commun. 2021. PMID: 34446722 Free PMC article. Clinical Trial.
50 results