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The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine.
Etchegaray JP, Chavez L, Huang Y, Ross KN, Choi J, Martinez-Pastor B, Walsh RM, Sommer CA, Lienhard M, Gladden A, Kugel S, Silberman DM, Ramaswamy S, Mostoslavsky G, Hochedlinger K, Goren A, Rao A, Mostoslavsky R. Etchegaray JP, et al. Among authors: mostoslavsky r, mostoslavsky g. Nat Cell Biol. 2015 May;17(5):545-57. doi: 10.1038/ncb3147. Epub 2015 Apr 27. Nat Cell Biol. 2015. PMID: 25915124 Free PMC article.
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6.
Mostoslavsky R, Chua KF, Lombard DB, Pang WW, Fischer MR, Gellon L, Liu P, Mostoslavsky G, Franco S, Murphy MM, Mills KD, Patel P, Hsu JT, Hong AL, Ford E, Cheng HL, Kennedy C, Nunez N, Bronson R, Frendewey D, Auerbach W, Valenzuela D, Karow M, Hottiger MO, Hursting S, Barrett JC, Guarente L, Mulligan R, Demple B, Yancopoulos GD, Alt FW. Mostoslavsky R, et al. Among authors: mostoslavsky g. Cell. 2006 Jan 27;124(2):315-29. doi: 10.1016/j.cell.2005.11.044. Cell. 2006. PMID: 16439206 Free article.
A mechanosensitive transcriptional mechanism that controls angiogenesis.
Mammoto A, Connor KM, Mammoto T, Yung CW, Huh D, Aderman CM, Mostoslavsky G, Smith LE, Ingber DE. Mammoto A, et al. Among authors: mostoslavsky g. Nature. 2009 Feb 26;457(7233):1103-8. doi: 10.1038/nature07765. Nature. 2009. PMID: 19242469 Free PMC article.
Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette.
Somers A, Jean JC, Sommer CA, Omari A, Ford CC, Mills JA, Ying L, Sommer AG, Jean JM, Smith BW, Lafyatis R, Demierre MF, Weiss DJ, French DL, Gadue P, Murphy GJ, Mostoslavsky G, Kotton DN. Somers A, et al. Among authors: mostoslavsky g. Stem Cells. 2010 Oct;28(10):1728-40. doi: 10.1002/stem.495. Stem Cells. 2010. PMID: 20715179 Free PMC article.
93 results