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Duvelisib treatment is associated with altered expression of apoptotic regulators that helps in sensitization of chronic lymphocytic leukemia cells to venetoclax (ABT-199).
Patel VM, Balakrishnan K, Douglas M, Tibbitts T, Xu EY, Kutok JL, Ayers M, Sarkar A, Guerrieri R, Wierda WG, O'Brien S, Jain N, Stern HM, Gandhi V. Patel VM, et al. Among authors: balakrishnan k. Leukemia. 2017 Sep;31(9):1872-1881. doi: 10.1038/leu.2016.382. Epub 2016 Dec 26. Leukemia. 2017. PMID: 28017967 Free PMC article. Clinical Trial.
Pharmacodynamics and proteomic analysis of acalabrutinib therapy: similarity of on-target effects to ibrutinib and rationale for combination therapy.
Patel VK, Lamothe B, Ayres ML, Gay J, Cheung JP, Balakrishnan K, Ivan C, Morse J, Nelson M, Keating MJ, Wierda WG, Marszalek JR, Gandhi V. Patel VK, et al. Among authors: balakrishnan k. Leukemia. 2018 Apr;32(4):920-930. doi: 10.1038/leu.2017.321. Epub 2017 Nov 3. Leukemia. 2018. PMID: 29099493 Free PMC article.
The micros in harmony: microRNA and microenvironment.
Balakrishnan K, Gandhi V. Balakrishnan K, et al. Leuk Lymphoma. 2011 Sep;52(9):1626-9. doi: 10.3109/10428194.2011.598252. Epub 2011 Jul 11. Leuk Lymphoma. 2011. PMID: 21740342 No abstract available.
CCL2 in chronic lymphocytic leukemia: a macro in microenvironment?
Gandhi V, Balakrishnan K. Gandhi V, et al. Among authors: balakrishnan k. Leuk Lymphoma. 2012 Oct;53(10):1849-50. doi: 10.3109/10428194.2012.688966. Epub 2012 May 21. Leuk Lymphoma. 2012. PMID: 22563818 Free PMC article. No abstract available.
703 results