Overmeer RM - Search Results

1

Sequential cancer mutations in cultured human intestinal stem cells.

Drost J, van Jaarsveld RH, Ponsioen B, Zimberlin C, van Boxtel R, Buijs A, Sachs N, Overmeer RM, Offerhaus GJ, Begthel H, Korving J, van de Wetering M, Schwank G, Logtenberg M, Cuppen E, Snippert HJ, Medema JP, Kops GJ, Clevers H. Drost J, et al. Among authors: overmeer rm. Nature. 2015 May 7;521(7550):43-7. doi: 10.1038/nature14415. Epub 2015 Apr 29. Nature. 2015. PMID: 25924068

2

Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening.

Verissimo CS, Overmeer RM, Ponsioen B, Drost J, Mertens S, Verlaan-Klink I, Gerwen BV, van der Ven M, Wetering MV, Egan DA, Bernards R, Clevers H, Bos JL, Snippert HJ. Verissimo CS, et al. Among authors: overmeer rm. Elife. 2016 Nov 15;5:e18489. doi: 10.7554/eLife.18489. Elife. 2016. PMID: 27845624 Free PMC article.

3

Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors.

Steinhart Z, Pavlovic Z, Chandrashekhar M, Hart T, Wang X, Zhang X, Robitaille M, Brown KR, Jaksani S, Overmeer R, Boj SF, Adams J, Pan J, Clevers H, Sidhu S, Moffat J, Angers S. Steinhart Z, et al. Nat Med. 2017 Jan;23(1):60-68. doi: 10.1038/nm.4219. Epub 2016 Nov 21. Nat Med. 2017. PMID: 27869803

4

Live imaging of cell division in 3D stem-cell organoid cultures.

Bolhaqueiro ACF, van Jaarsveld RH, Ponsioen B, Overmeer RM, Snippert HJ, Kops GJPL. Bolhaqueiro ACF, et al. Among authors: overmeer rm. Methods Cell Biol. 2018;145:91-106. doi: 10.1016/bs.mcb.2018.03.016. Epub 2018 Apr 22. Methods Cell Biol. 2018. PMID: 29957217

5

Medium-Throughput Drug- and Radiotherapy Screening Assay using Patient-Derived Organoids.

Putker M, Millen R, Overmeer R, Driehuis E, Zandvliet MMJM, Clevers H, Boj SF, Li QX. Putker M, et al. J Vis Exp. 2021 Apr 30;(170). doi: 10.3791/62495. J Vis Exp. 2021. PMID: 33999032

6

Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer.

Mertens S, Huismans MA, Verissimo CS, Ponsioen B, Overmeer R, Proost N, van Tellingen O, van de Ven M, Begthel H, Boj SF, Clevers H, Roodhart JML, Bos JL, Snippert HJG. Mertens S, et al. Cell Rep. 2023 Apr 25;42(4):112324. doi: 10.1016/j.celrep.2023.112324. Epub 2023 Mar 30. Cell Rep. 2023. PMID: 37000626 Free article.

7

Corrigendum: Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors.

Steinhart Z, Pavlovic Z, Chandrashekhar M, Hart T, Wang X, Zhang X, Robitaille M, Brown KR, Jaksani S, Overmeer R, Boj SF, Adams J, Pan J, Clevers H, Sidhu S, Moffat J, Angers S. Steinhart Z, et al. Nat Med. 2017 Nov 7;23(11):1384. doi: 10.1038/nm1117-1384d. Nat Med. 2017. PMID: 29117169

8

Replication protein A safeguards genome integrity by controlling NER incision events.

Overmeer RM, Moser J, Volker M, Kool H, Tomkinson AE, van Zeeland AA, Mullenders LH, Fousteri M. Overmeer RM, et al. J Cell Biol. 2011 Feb 7;192(3):401-15. doi: 10.1083/jcb.201006011. Epub 2011 Jan 31. J Cell Biol. 2011. PMID: 21282463 Free PMC article.

9

Replication factor C recruits DNA polymerase delta to sites of nucleotide excision repair but is not required for PCNA recruitment.

Overmeer RM, Gourdin AM, Giglia-Mari A, Kool H, Houtsmuller AB, Siegal G, Fousteri MI, Mullenders LH, Vermeulen W. Overmeer RM, et al. Mol Cell Biol. 2010 Oct;30(20):4828-39. doi: 10.1128/MCB.00285-10. Epub 2010 Aug 16. Mol Cell Biol. 2010. PMID: 20713449 Free PMC article.

10

Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells.

Ogi T, Limsirichaikul S, Overmeer RM, Volker M, Takenaka K, Cloney R, Nakazawa Y, Niimi A, Miki Y, Jaspers NG, Mullenders LH, Yamashita S, Fousteri MI, Lehmann AR. Ogi T, et al. Among authors: overmeer rm. Mol Cell. 2010 Mar 12;37(5):714-27. doi: 10.1016/j.molcel.2010.02.009. Mol Cell. 2010. PMID: 20227374 Free article.

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