Snippert HJ - Search Results

1

Sequential cancer mutations in cultured human intestinal stem cells.

Drost J, van Jaarsveld RH, Ponsioen B, Zimberlin C, van Boxtel R, Buijs A, Sachs N, Overmeer RM, Offerhaus GJ, Begthel H, Korving J, van de Wetering M, Schwank G, Logtenberg M, Cuppen E, Snippert HJ, Medema JP, Kops GJ, Clevers H. Drost J, et al. Among authors: snippert hj. Nature. 2015 May 7;521(7550):43-7. doi: 10.1038/nature14415. Epub 2015 Apr 29. Nature. 2015. PMID: 25924068

2

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche.

Sato T, Vries RG, Snippert HJ, van de Wetering M, Barker N, Stange DE, van Es JH, Abo A, Kujala P, Peters PJ, Clevers H. Sato T, et al. Among authors: snippert hj. Nature. 2009 May 14;459(7244):262-5. doi: 10.1038/nature07935. Epub 2009 Mar 29. Nature. 2009. PMID: 19329995

3

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts.

Sato T, van Es JH, Snippert HJ, Stange DE, Vries RG, van den Born M, Barker N, Shroyer NF, van de Wetering M, Clevers H. Sato T, et al. Among authors: snippert hj. Nature. 2011 Jan 20;469(7330):415-8. doi: 10.1038/nature09637. Epub 2010 Nov 28. Nature. 2011. PMID: 21113151 Free PMC article.

4

Tracking adult stem cells.

Snippert HJ, Clevers H. Snippert HJ, et al. EMBO Rep. 2011 Feb;12(2):113-22. doi: 10.1038/embor.2010.216. Epub 2011 Jan 21. EMBO Rep. 2011. PMID: 21252944 Free PMC article. Review.

5

A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal cancer progression.

Fumagalli A, Suijkerbuijk SJE, Begthel H, Beerling E, Oost KC, Snippert HJ, van Rheenen J, Drost J. Fumagalli A, et al. Among authors: snippert hj. Nat Protoc. 2018 Feb;13(2):235-247. doi: 10.1038/nprot.2017.137. Epub 2018 Jan 4. Nat Protoc. 2018. PMID: 29300390

6

Live imaging of cell division in 3D stem-cell organoid cultures.

Bolhaqueiro ACF, van Jaarsveld RH, Ponsioen B, Overmeer RM, Snippert HJ, Kops GJPL. Bolhaqueiro ACF, et al. Among authors: snippert hj. Methods Cell Biol. 2018;145:91-106. doi: 10.1016/bs.mcb.2018.03.016. Epub 2018 Apr 22. Methods Cell Biol. 2018. PMID: 29957217

7

Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas.

Schepers AG, Snippert HJ, Stange DE, van den Born M, van Es JH, van de Wetering M, Clevers H. Schepers AG, et al. Among authors: snippert hj. Science. 2012 Aug 10;337(6095):730-5. doi: 10.1126/science.1224676. Epub 2012 Aug 1. Science. 2012. PMID: 22855427

8

Biased competition between Lgr5 intestinal stem cells driven by oncogenic mutation induces clonal expansion.

Snippert HJ, Schepers AG, van Es JH, Simons BD, Clevers H. Snippert HJ, et al. EMBO Rep. 2014 Jan;15(1):62-9. doi: 10.1002/embr.201337799. Epub 2013 Dec 15. EMBO Rep. 2014. PMID: 24355609 Free PMC article.

9

Intestinal crypt homeostasis revealed at single-stem-cell level by in vivo live imaging.

Ritsma L, Ellenbroek SIJ, Zomer A, Snippert HJ, de Sauvage FJ, Simons BD, Clevers H, van Rheenen J. Ritsma L, et al. Among authors: snippert hj. Nature. 2014 Mar 20;507(7492):362-365. doi: 10.1038/nature12972. Epub 2014 Feb 16. Nature. 2014. PMID: 24531760 Free PMC article.

10

Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening.

Verissimo CS, Overmeer RM, Ponsioen B, Drost J, Mertens S, Verlaan-Klink I, Gerwen BV, van der Ven M, Wetering MV, Egan DA, Bernards R, Clevers H, Bos JL, Snippert HJ. Verissimo CS, et al. Among authors: snippert hj. Elife. 2016 Nov 15;5:e18489. doi: 10.7554/eLife.18489. Elife. 2016. PMID: 27845624 Free PMC article.

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