DeSilva B - Search Results

1

Development and Fit-for-Purpose Validation of a Soluble Human Programmed Death-1 Protein Assay.

Ni YG, Yuan X, Newitt JA, Peterson JE, Gleason CR, Haulenbeek J, Santockyte R, Lafont V, Marsilio F, Neely RJ, DeSilva B, Piccoli SP. Ni YG, et al. Among authors: desilva b. AAPS J. 2015 Jul;17(4):976-87. doi: 10.1208/s12248-015-9762-4. Epub 2015 May 1. AAPS J. 2015. PMID: 25924887 Free PMC article.

2

Accelerating Regulated Bioanalysis for Biotherapeutics: Case Examples Using a Microfluidic Ligand Binding Assay Platform.

Liu R, Hoffpauir B, Chilewski SD, Gamberdella J, Kavita U, Duo J, Gleason C, Zhang Y, Pillutla R, DeSilva B, Hamuro L. Liu R, et al. Among authors: desilva b. AAPS J. 2017 Jan;19(1):82-91. doi: 10.1208/s12248-016-0006-z. Epub 2016 Oct 27. AAPS J. 2017. PMID: 27796911

3

Surface plasmon resonance as a tool for ligand-binding assay reagent characterization in bioanalysis of biotherapeutics.

Duo J, Bruno J, Kozhich A, David-Brown D, Luo L, Kwok S, Santockyte R, Haulenbeek J, Liu R, Hamuro L, Peterson JE, Piccoli S, DeSilva B, Pillutla R, Zhang YJ. Duo J, et al. Among authors: desilva b. Bioanalysis. 2018 Apr 1;10(8):559-576. doi: 10.4155/bio-2017-0271. Epub 2018 Apr 27. Bioanalysis. 2018. PMID: 29701071

4

Development and validation of an LC-MS/MS assay for the quantitation of a PEGylated anti-CD28 domain antibody in human serum: overcoming interference from antidrug antibodies and soluble target.

Gong C, Zeng J, Akinsanya B, Jiang H, Mora J, Chilewski S, Gambardella J, Allentoff A, Gleason C, Aubry AF, DeSilva BS, Arnold ME. Gong C, et al. Among authors: desilva bs. Bioanalysis. 2014 Sep;6(18):2371-83. doi: 10.4155/bio.14.181. Bioanalysis. 2014. PMID: 25384590

5

Development and characterization of a pre-treatment procedure to eliminate human monoclonal antibody therapeutic drug and matrix interference in cell-based functional neutralizing antibody assays.

Xu W, Jiang H, Titsch C, Haulenbeek JR, Pillutla RC, Aubry AF, DeSilva BS, Arnold ME, Zeng J, Dodge RW. Xu W, et al. J Immunol Methods. 2015 Jan;416:94-104. doi: 10.1016/j.jim.2014.11.005. Epub 2014 Nov 8. J Immunol Methods. 2015. PMID: 25445325

6

Addressing matrix effects in ligand-binding assays through the use of new reagents and technology.

Chilewski SD, Mora JR, Gleason C, DeSilva B. Chilewski SD, et al. Among authors: desilva b. Bioanalysis. 2014 Apr;6(8):1059-67. doi: 10.4155/bio.14.75. Bioanalysis. 2014. PMID: 24830890

7

Development and validation of a functional cell-based neutralizing antibody assay for ipilimumab.

Xu W, Cummings J, Sank M, Juhel M, Li X, Gleason C, DeSilva BS, Dodge RW, Pillutla R. Xu W, et al. Bioanalysis. 2018 Aug 1;10(16):1273-1287. doi: 10.4155/bio-2018-0109. Epub 2018 Jun 27. Bioanalysis. 2018. PMID: 29947549

8

Targeting an acid labile aspartyl-prolyl amide bond as a viable alternative to trypsin digestion to generate a surrogate peptide for LC-MS/MS analysis.

Fung EN, Zambito F, Haulenbeek J, Piccoli SP, Zhang Y, DeSilva B, Arnold M, Kozhich A. Fung EN, et al. Among authors: desilva b. Bioanalysis. 2014;6(22):2985-98. doi: 10.4155/bio.14.182. Bioanalysis. 2014. PMID: 25496253

9

An integrated multiplatform bioanalytical strategy for antibody-drug conjugates: a novel case study.

Myler H, Rangan VS, Wang J, Kozhich A, Cummings JA, Neely R, Dail D, Liu A, Wang B, Vezina HE, Freebern W, Sung MC, Passmore D, Deshpande S, Kempe T, Gu H, Saewert M, Manney A, Lute J, Zambito F, Wong RL, Piccoli SP, Aubry AF, Pillutla R, Arnold M, DeSilva B. Myler H, et al. Among authors: desilva b. Bioanalysis. 2015;7(13):1569-82. doi: 10.4155/bio.15.80. Bioanalysis. 2015. PMID: 26226308

10

Bead-extraction and heat-dissociation (BEHD): A novel way to overcome drug and matrix interference in immunogenicity testing.

Xu W, Sank M, Cummings J, Carl S, Juhel M, Gleason C, Dodge R, DeSilva BS, Kolaitis G, Pillutla R. Xu W, et al. J Immunol Methods. 2018 Nov;462:34-41. doi: 10.1016/j.jim.2018.08.003. Epub 2018 Aug 9. J Immunol Methods. 2018. PMID: 30099014

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