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Myristyl trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are surface-active small molecule dynamin inhibitors that block endocytosis mediated by dynamin I or dynamin II.
Quan A, McGeachie AB, Keating DJ, van Dam EM, Rusak J, Chau N, Malladi CS, Chen C, McCluskey A, Cousin MA, Robinson PJ. Quan A, et al. Among authors: keating dj. Mol Pharmacol. 2007 Dec;72(6):1425-39. doi: 10.1124/mol.107.034207. Epub 2007 Aug 16. Mol Pharmacol. 2007. PMID: 17702890
Pyrimidyn compounds: dual-action small molecule pyrimidine-based dynamin inhibitors.
McGeachie AB, Odell LR, Quan A, Daniel JA, Chau N, Hill TA, Gorgani NN, Keating DJ, Cousin MA, van Dam EM, Mariana A, Whiting A, Perera S, Novelle A, Young KA, Deane FM, Gilbert J, Sakoff JA, Chircop M, McCluskey A, Robinson PJ. McGeachie AB, et al. Among authors: keating dj. ACS Chem Biol. 2013 Jul 19;8(7):1507-18. doi: 10.1021/cb400137p. Epub 2013 May 30. ACS Chem Biol. 2013. PMID: 23642287
110 results