Overholser JP - Search Results

1

HER-3 peptide vaccines/mimics: Combined therapy with IGF-1R, HER-2, and HER-1 peptides induces synergistic antitumor effects against breast and pancreatic cancer cells.

Miller MJ, Foy KC, Overholser JP, Nahta R, Kaumaya PT. Miller MJ, et al. Among authors: overholser jp. Oncoimmunology. 2014 Dec 21;3(11):e956012. doi: 10.4161/21624011.2014.956012. eCollection 2014 Nov. Oncoimmunology. 2014. PMID: 25941588 Free PMC article.

2

Peptide vaccines and peptidomimetics of EGFR (HER-1) ligand binding domain inhibit cancer cell growth in vitro and in vivo.

Foy KC, Wygle RM, Miller MJ, Overholser JP, Bekaii-Saab T, Kaumaya PT. Foy KC, et al. Among authors: overholser jp. J Immunol. 2013 Jul 1;191(1):217-27. doi: 10.4049/jimmunol.1300231. Epub 2013 May 22. J Immunol. 2013. PMID: 23698748 Free PMC article.

3

IGF-1R peptide vaccines/mimics inhibit the growth of BxPC3 and JIMT-1 cancer cells and exhibit synergistic antitumor effects with HER-1 and HER-2 peptides.

Foy KC, Miller MJ, Overholser J, Donnelly SM, Nahta R, Kaumaya PT. Foy KC, et al. Oncoimmunology. 2014 Dec 21;3(11):e956005. doi: 10.4161/21624011.2014.956005. eCollection 2014 Nov. Oncoimmunology. 2014. PMID: 25941587 Free PMC article.

4

Anti-Tumor Effects of Peptide Therapeutic and Peptide Vaccine Antibody Co-targeting HER-1 and HER-2 in Esophageal Cancer (EC) and HER-1 and IGF-1R in Triple-Negative Breast Cancer (TNBC).

Overholser J, Ambegaokar KH, Eze SM, Sanabria-Figueroa E, Nahta R, Bekaii-Saab T, Kaumaya PT. Overholser J, et al. Vaccines (Basel). 2015 Jul 6;3(3):519-43. doi: 10.3390/vaccines3030519. Vaccines (Basel). 2015. PMID: 26350593 Free PMC article.

5

Phase I Immunotherapy Trial with Two Chimeric HER-2 B-Cell Peptide Vaccines Emulsified in Montanide ISA 720VG and Nor-MDP Adjuvant in Patients with Advanced Solid Tumors.

Bekaii-Saab T, Wesolowski R, Ahn DH, Wu C, Mortazavi A, Lustberg M, Ramaswamy B, Fowler J, Wei L, Overholser J, Kaumaya PTP. Bekaii-Saab T, et al. Clin Cancer Res. 2019 Jun 15;25(12):3495-3507. doi: 10.1158/1078-0432.CCR-18-3997. Epub 2019 Feb 25. Clin Cancer Res. 2019. PMID: 30804020 Free PMC article. Clinical Trial.

6

Immunogenicity and antitumor efficacy of a novel human PD-1 B-cell vaccine (PD1-Vaxx) and combination immunotherapy with dual trastuzumab/pertuzumab-like HER-2 B-cell epitope vaccines (B-Vaxx) in a syngeneic mouse model.

Kaumaya PTP, Guo L, Overholser J, Penichet ML, Bekaii-Saab T. Kaumaya PTP, et al. Oncoimmunology. 2020 Oct 1;9(1):1818437. doi: 10.1080/2162402X.2020.1818437. Oncoimmunology. 2020. PMID: 33117602 Free PMC article.

7

Preclinical Studies of a Novel Human PD-1 B-Cell Peptide Cancer Vaccine PD1-Vaxx From BALB/c Mice to Beagle Dogs and to Non-Human Primates (Cynomolgus Monkeys).

Guo L, Overholser J, Good AJ, Ede NJ, Kaumaya PTP. Guo L, et al. Front Oncol. 2022 May 13;12:826566. doi: 10.3389/fonc.2022.826566. eCollection 2022. Front Oncol. 2022. PMID: 35646678 Free PMC article.

8

A newly discovered PD-L1 B-cell epitope peptide vaccine (PDL1-Vaxx) exhibits potent immune responses and effective anti-tumor immunity in multiple syngeneic mice models and (synergizes) in combination with a dual HER-2 B-cell vaccine (B-Vaxx).

Guo L, Overholser J, Darby H, Ede NJ, Kaumaya PTP. Guo L, et al. Oncoimmunology. 2022 Oct 5;11(1):2127691. doi: 10.1080/2162402X.2022.2127691. eCollection 2022. Oncoimmunology. 2022. PMID: 36211807 Free PMC article.

9

Magnetic Fluorescent Bead-Based Dual-Reporter Flow Analysis of PDL1-Vaxx Peptide Vaccine-Induced Antibody Blockade of the PD-1/PD-L1 Interaction.

Overholser J, Guo L, Kaumaya PTP. Overholser J, et al. J Vis Exp. 2023 Jul 7;(197). doi: 10.3791/65467. J Vis Exp. 2023. PMID: 37486131

10

Mitochondrial VDAC1: A Potential Therapeutic Target of Inflammation-Related Diseases and Clinical Opportunities.

Hu H, Guo L, Overholser J, Wang X. Hu H, et al. Cells. 2022 Oct 10;11(19):3174. doi: 10.3390/cells11193174. Cells. 2022. PMID: 36231136 Free PMC article. Review.

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