Shah D - Search Results

1

Prediction of pH dependent absorption using in vitro, in silico, and in vivo rat models: Early liability assessment during lead optimization.

Saxena A, Shah D, Padmanabhan S, Gautam SS, Chowan GS, Mandlekar S, Desikan S. Saxena A, et al. Among authors: shah d. Eur J Pharm Sci. 2015 Aug 30;76:173-80. doi: 10.1016/j.ejps.2015.05.006. Epub 2015 May 8. Eur J Pharm Sci. 2015. PMID: 25960252

2

A systematic evaluation of solubility enhancing excipients to enable the generation of permeability data for poorly soluble compounds in Caco-2 model.

Shah D, Paruchury S, Matta M, Chowan G, Subramanian M, Saxena A, Soars MG, Herbst J, Haskell R, Marathe P, Mandlekar S. Shah D, et al. Drug Metab Lett. 2014;8(2):109-18. doi: 10.2174/1872312808666141127113055. Drug Metab Lett. 2014. PMID: 25429513

3

Absolute quantification of imipramine and its metabolites in vivo utilizing calibrators from radiolabeled in vitro incubations.

Bhutani P, Shah D, Varkhede N, Mandlekar S, Chacko S, Subramanian M. Bhutani P, et al. Among authors: shah d. Bioanalysis. 2016 Feb;8(4):297-309. doi: 10.4155/bio.15.259. Epub 2016 Feb 5. Bioanalysis. 2016. PMID: 26847656

4

Synthesis, Structure-Activity Relationships, and In Vivo Evaluation of Novel Tetrahydropyran-Based Thiodisaccharide Mimics as Galectin-3 Inhibitors.

Xu L, Hartz RA, Beno BR, Ghosh K, Shukla JK, Kumar A, Patel D, Kalidindi N, Lemos N, Gautam SS, Kumar A, Ellsworth BA, Shah D, Sale H, Cheng D, Regueiro-Ren A. Xu L, et al. Among authors: shah d. J Med Chem. 2021 May 27;64(10):6634-6655. doi: 10.1021/acs.jmedchem.0c02001. Epub 2021 May 14. J Med Chem. 2021. PMID: 33988358

5

Evaluation of Encequidar as An Intestinal P-gp and BCRP Specific Inhibitor to Assess the Role of Intestinal P-gp and BCRP in Drug-Drug Interactions.

Chu J, Panfen E, Wang L, Marino A, Chen XQ, Fancher RM, Landage R, Patil O, Desai SD, Shah D, Xue Y, Sinz M, Shen H. Chu J, et al. Among authors: shah d. Pharm Res. 2023 Nov;40(11):2567-2584. doi: 10.1007/s11095-023-03563-4. Epub 2023 Jul 31. Pharm Res. 2023. PMID: 37523014

6

Exploring monocyclic core: Discovery of pyrrol-2-one derivatives as a new series of potent MCHR1 antagonists with in vivo efficacy.

A M Subbaiah M, Mandal U, Patankar V, Bhaskaran S, Nutakki R, Rami B, Shah DP, Mahammad S, Murphy BJ, Huang C, Robl JA, Washburn WN. A M Subbaiah M, et al. Eur J Med Chem. 2024 Oct 5;276:116686. doi: 10.1016/j.ejmech.2024.116686. Epub 2024 Jul 20. Eur J Med Chem. 2024. PMID: 39053192

7

Identification of Monosaccharide Derivatives as Potent, Selective, and Orally Bioavailable Inhibitors of Human and Mouse Galectin-3.

Liu C, Jalagam PR, Feng J, Wang W, Raja T, Sura MR, Manepalli RKVLP, Aliphedi BR, Medavarapu S, Nair SK, Muthalagu V, Natesan R, Gupta A, Beno B, Panda M, Ghosh K, Shukla JK, Sale H, Haldar P, Kalidindi N, Shah D, Patel D, Mathur A, Ellsworth BA, Cheng D, Regueiro-Ren A. Liu C, et al. Among authors: shah d. J Med Chem. 2022 Aug 25;65(16):11084-11099. doi: 10.1021/acs.jmedchem.2c00517. Epub 2022 Aug 15. J Med Chem. 2022. PMID: 35969688

8

Effect of Gold Nanoparticles on the Conformation of Bovine Serum Albumin: Insights from CD Spectroscopic Analysis and Molecular Dynamics Simulations.

Kaumbekova S, Sakaguchi N, Shah D, Umezawa M. Kaumbekova S, et al. Among authors: shah d. ACS Omega. 2024 Dec 3;9(50):49283-49292. doi: 10.1021/acsomega.4c06409. eCollection 2024 Dec 17. ACS Omega. 2024. PMID: 39713703 Free PMC article.

9

Role of Image-Free Robotic-Assisted Technology in Enhancing Accuracy of Implant Sizing for Total Knee Arthroplasty.

Londhe SB, Patel K, Baranwal G, Shah A, Shah D. Londhe SB, et al. Among authors: shah d. Cureus. 2024 Nov 22;16(11):e74256. doi: 10.7759/cureus.74256. eCollection 2024 Nov. Cureus. 2024. PMID: 39712684 Free PMC article.

10

mHealth Engagement for Antiretroviral Medication Adherence Among People With HIV and Substance Use Disorders: Observational Study.

Mi RZ, Yang EF, Tahk A, Tarfa A, Cotter LM, Lu L, Yang S, Gustafson DH Sr, Westergaard R, Shah D. Mi RZ, et al. Among authors: shah d. J Med Internet Res. 2024 Dec 20;26:e57774. doi: 10.2196/57774. J Med Internet Res. 2024. PMID: 39705693 Free article.

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