Heise C - Search Results

1

Discovery of bicyclic pyrazoles as class III histone deacetylase SIRT1 and SIRT2 inhibitors.

Therrien E, Larouche G, Nguyen N, Rahil J, Lemieux AM, Li Z, Fournel M, Yan TP, Landry AJ, Lefebvre S, Wang JJ, MacBeth K, Heise C, Nguyen A, Besterman JM, Déziel R, Wahhab A. Therrien E, et al. Among authors: heise c. Bioorg Med Chem Lett. 2015 Jun 15;25(12):2514-8. doi: 10.1016/j.bmcl.2015.04.068. Epub 2015 Apr 28. Bioorg Med Chem Lett. 2015. PMID: 25971769

2

Azacitidine and decitabine have different mechanisms of action in non-small cell lung cancer cell lines.

Nguyen AN, Hollenbach PW, Richard N, Luna-Moran A, Brady H, Heise C, MacBeth KJ. Nguyen AN, et al. Among authors: heise c. Lung Cancer (Auckl). 2010 Sep 9;1:119-140. doi: 10.2147/LCTT.S11726. eCollection 2010. Lung Cancer (Auckl). 2010. PMID: 28210112 Free PMC article.

3

A comparison of azacitidine and decitabine activities in acute myeloid leukemia cell lines.

Hollenbach PW, Nguyen AN, Brady H, Williams M, Ning Y, Richard N, Krushel L, Aukerman SL, Heise C, MacBeth KJ. Hollenbach PW, et al. Among authors: heise c. PLoS One. 2010 Feb 2;5(2):e9001. doi: 10.1371/journal.pone.0009001. PLoS One. 2010. PMID: 20126405 Free PMC article.

4

The class-I HDAC inhibitor MGCD0103 induces apoptosis in Hodgkin lymphoma cell lines and synergizes with proteasome inhibitors by an HDAC6-independent mechanism.

Buglio D, Mamidipudi V, Khaskhely NM, Brady H, Heise C, Besterman J, Martell RE, MacBeth K, Younes A. Buglio D, et al. Among authors: heise c. Br J Haematol. 2010 Nov;151(4):387-96. doi: 10.1111/j.1365-2141.2010.08342.x. Epub 2010 Sep 29. Br J Haematol. 2010. PMID: 20880107 Free PMC article.

5

Design and structure-activity relationship of 3-benzimidazol-2-yl-1H-indazoles as inhibitors of receptor tyrosine kinases.

McBride CM, Renhowe PA, Heise C, Jansen JM, Lapointe G, Ma S, Piñeda R, Vora J, Wiesmann M, Shafer CM. McBride CM, et al. Among authors: heise c. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3595-9. doi: 10.1016/j.bmcl.2006.03.069. Epub 2006 Apr 5. Bioorg Med Chem Lett. 2006. PMID: 16603352

6

Design, structure-activity relationships and in vivo characterization of 4-amino-3-benzimidazol-2-ylhydroquinolin-2-ones: a novel class of receptor tyrosine kinase inhibitors.

Renhowe PA, Pecchi S, Shafer CM, Machajewski TD, Jazan EM, Taylor C, Antonios-McCrea W, McBride CM, Frazier K, Wiesmann M, Lapointe GR, Feucht PH, Warne RL, Heise CC, Menezes D, Aardalen K, Ye H, He M, Le V, Vora J, Jansen JM, Wernette-Hammond ME, Harris AL. Renhowe PA, et al. Among authors: heise cc. J Med Chem. 2009 Jan 22;52(2):278-92. doi: 10.1021/jm800790t. J Med Chem. 2009. PMID: 19113866

7

Histone deacetylase inhibitor MGCD0103 synergizes with gemcitabine in human pancreatic cells.

Sung V, Richard N, Brady H, Maier A, Kelter G, Heise C. Sung V, et al. Among authors: heise c. Cancer Sci. 2011 Jun;102(6):1201-7. doi: 10.1111/j.1349-7006.2011.01921.x. Epub 2011 Apr 18. Cancer Sci. 2011. PMID: 21375679 Free article.

8

Increased cellular accumulation and distribution of amrubicin contribute to its activity in anthracycline-resistant cancer cells.

Mamidipudi V, Shi T, Brady H, Surapaneni S, Chopra R, Aukerman SL, Heise C, Sung V. Mamidipudi V, et al. Among authors: heise c. Cancer Chemother Pharmacol. 2012 Apr;69(4):965-76. doi: 10.1007/s00280-011-1782-x. Epub 2011 Nov 26. Cancer Chemother Pharmacol. 2012. PMID: 22120960

9

Recombinant interleukin-2 significantly augments activity of rituximab in human tumor xenograft models of B-cell non-Hodgkin lymphoma.

Lopes de Menezes DE, Denis-Mize K, Tang Y, Ye H, Kunich JC, Garrett EN, Peng J, Cousens LS, Gelb AB, Heise C, Wilson SE, Jallal B, Aukerman SL. Lopes de Menezes DE, et al. Among authors: heise c. J Immunother. 2007 Jan;30(1):64-74. doi: 10.1097/01.cji.0000211315.21116.07. J Immunother. 2007. PMID: 17198084

10

Single-agent lenalidomide in relapsed/refractory mantle cell lymphoma: results from a UK phase II study suggest activity and possible gender differences.

Eve HE, Carey S, Richardson SJ, Heise CC, Mamidipudi V, Shi T, Radford JA, Auer RL, Bullard SH, Rule SA. Eve HE, et al. Among authors: heise cc. Br J Haematol. 2012 Oct;159(2):154-63. doi: 10.1111/bjh.12008. Epub 2012 Aug 9. Br J Haematol. 2012. PMID: 22881386 Free article. Clinical Trial.

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