Tretter T - Search Results

1

Activated human B cells induce inflammatory fibroblasts with cartilage-destructive properties and become functionally suppressed in return.

Störch H, Zimmermann B, Resch B, Tykocinski LO, Moradi B, Horn P, Kaya Z, Blank N, Rehart S, Thomsen M, Lorenz HM, Neumann E, Tretter T. Störch H, et al. Among authors: tretter t. Ann Rheum Dis. 2016 May;75(5):924-32. doi: 10.1136/annrheumdis-2014-206965. Epub 2015 May 18. Ann Rheum Dis. 2016. PMID: 25985971

2

Synovial Fibroblasts Selectively Suppress Th1 Cell Responses through IDO1-Mediated Tryptophan Catabolism.

Tykocinski LO, Lauffer AM, Bohnen A, Kaul NC, Krienke S, Tretter T, Adam I, Mohapatra SR, Saikali P, Löhning M, Neidhart M, Gay S, Oezen I, Platten M, Opitz CA, Lorenz HM. Tykocinski LO, et al. Among authors: tretter t. J Immunol. 2017 Apr 15;198(8):3109-3117. doi: 10.4049/jimmunol.1600600. Epub 2017 Mar 6. J Immunol. 2017. PMID: 28264972

3

Hypoxia decreases the T helper cell-suppressive capacity of synovial fibroblasts by downregulating IDO1-mediated tryptophan metabolism.

Kaul NC, Mohapatra SR, Adam I, Tucher C, Tretter T, Opitz CA, Lorenz HM, Tykocinski LO. Kaul NC, et al. Among authors: tretter t. Rheumatology (Oxford). 2020 May 1;59(5):1148-1158. doi: 10.1093/rheumatology/kez587. Rheumatology (Oxford). 2020. PMID: 31846032

4

Proinflammatory T cell polarization is already present in patients with early knee osteoarthritis.

Rosshirt N, Trauth R, Platzer H, Tripel E, Nees TA, Lorenz HM, Tretter T, Moradi B. Rosshirt N, et al. Among authors: tretter t. Arthritis Res Ther. 2021 Jan 22;23(1):37. doi: 10.1186/s13075-020-02410-w. Arthritis Res Ther. 2021. PMID: 33482899 Free PMC article.

5

Increase of aerobic glycolysis mediated by activated T helper cells drives synovial fibroblasts towards an inflammatory phenotype: new targets for therapy?

Kvacskay P, Yao N, Schnotz JH, Scarpone R, Carvalho RA, Klika KD, Merkt W, Tretter T, Lorenz HM, Tykocinski LO. Kvacskay P, et al. Among authors: tretter t. Arthritis Res Ther. 2021 Feb 15;23(1):56. doi: 10.1186/s13075-021-02437-7. Arthritis Res Ther. 2021. PMID: 33588937 Free PMC article.

6

Targeting of Janus Kinases Limits Pro-Inflammatory but Also Immunosuppressive Circuits in the Crosstalk between Synovial Fibroblasts and Lymphocytes.

Yao N, Tretter T, Kvacskay P, Merkt W, Blank N, Lorenz HM, Tykocinski LO. Yao N, et al. Among authors: tretter t. Biomedicines. 2021 Oct 8;9(10):1413. doi: 10.3390/biomedicines9101413. Biomedicines. 2021. PMID: 34680530 Free PMC article.

7

Interleukin-4 supports interleukin-12-induced proliferation and interferon-gamma secretion in human activated lymphoblasts and T helper type 1 cells.

Kriegel MA, Tretter T, Blank N, Schiller M, Gabler C, Winkler S, Kalden JR, Lorenz HM. Kriegel MA, et al. Among authors: tretter t. Immunology. 2006 Sep;119(1):43-53. doi: 10.1111/j.1365-2567.2006.02404.x. Epub 2006 Jun 6. Immunology. 2006. PMID: 16762027 Free PMC article.

8

Impaired suppressive capacity of activation-induced regulatory B cells in systemic lupus erythematosus.

Gao N, Dresel J, Eckstein V, Gellert R, Störch H, Venigalla RK, Schwenger V, Max R, Blank N, Lorenz HM, Tretter T. Gao N, et al. Among authors: tretter t. Arthritis Rheumatol. 2014 Oct;66(10):2849-61. doi: 10.1002/art.38742. Arthritis Rheumatol. 2014. PMID: 24942956

9

Effect of JAK Inhibition on the Induction of Proinflammatory HLA-DR+CD90+ Rheumatoid Arthritis Synovial Fibroblasts by Interferon-γ.

Zhao S, Grieshaber-Bouyer R, Rao DA, Kolb P, Chen H, Andreeva I, Tretter T, Lorenz HM, Watzl C, Wabnitz G, Tykocinski LO, Merkt W. Zhao S, et al. Among authors: tretter t. Arthritis Rheumatol. 2022 Mar;74(3):441-452. doi: 10.1002/art.41958. Arthritis Rheumatol. 2022. PMID: 34435471 Free PMC article.

10

Reduced CD4+,CD25- T cell sensitivity to the suppressive function of CD4+,CD25high,CD127 -/low regulatory T cells in patients with active systemic lupus erythematosus.

Venigalla RK, Tretter T, Krienke S, Max R, Eckstein V, Blank N, Fiehn C, Ho AD, Lorenz HM. Venigalla RK, et al. Among authors: tretter t. Arthritis Rheum. 2008 Jul;58(7):2120-30. doi: 10.1002/art.23556. Arthritis Rheum. 2008. PMID: 18576316 Free article.

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