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Increased stiffness is the major early abnormality in a pig model of severe aortic stenosis and predisposes to congestive heart failure in the absence of systolic dysfunction.
Ishikawa K, Aguero J, Oh JG, Hammoudi N, Fish LA, Leonardson L, Picatoste B, Santos-Gallego CG, Fish KM, Hajjar RJ. Ishikawa K, et al. Among authors: aguero j. J Am Heart Assoc. 2015 May 20;4(5):e001925. doi: 10.1161/JAHA.115.001925. J Am Heart Assoc. 2015. PMID: 25994443 Free PMC article.
Cardiac I-1c overexpression with reengineered AAV improves cardiac function in swine ischemic heart failure.
Ishikawa K, Fish KM, Tilemann L, Rapti K, Aguero J, Santos-Gallego CG, Lee A, Karakikes I, Xie C, Akar FG, Shimada YJ, Gwathmey JK, Asokan A, McPhee S, Samulski J, Samulski RJ, Sigg DC, Weber T, Kranias EG, Hajjar RJ. Ishikawa K, et al. Among authors: aguero j. Mol Ther. 2014 Dec;22(12):2038-2045. doi: 10.1038/mt.2014.127. Epub 2014 Jul 15. Mol Ther. 2014. PMID: 25023328 Free PMC article.
Characterization of right ventricular remodeling and failure in a chronic pulmonary hypertension model.
Aguero J, Ishikawa K, Hadri L, Santos-Gallego C, Fish K, Hammoudi N, Chaanine A, Torquato S, Naim C, Ibanez B, Pereda D, García-Alvarez A, Fuster V, Sengupta PP, Leopold JA, Hajjar RJ. Aguero J, et al. Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1204-15. doi: 10.1152/ajpheart.00246.2014. Epub 2014 Aug 22. Am J Physiol Heart Circ Physiol. 2014. PMID: 25158063 Free PMC article.
Stem cell factor gene transfer improves cardiac function after myocardial infarction in swine.
Ishikawa K, Fish K, Aguero J, Yaniz-Galende E, Jeong D, Kho C, Tilemann L, Fish L, Liang L, Eltoukhy AA, Anderson DG, Zsebo K, Costa KD, Hajjar RJ. Ishikawa K, et al. Among authors: aguero j. Circ Heart Fail. 2015 Jan;8(1):167-74. doi: 10.1161/CIRCHEARTFAILURE.114.001711. Epub 2014 Oct 23. Circ Heart Fail. 2015. PMID: 25342737 Free PMC article.
Reply to "Letter to the editor: Characterizing preclinical model of ischemic heart failure: difference between LAD and LCx infarctions".
Ishikawa K, Aguero J, Tilemann L, Ladage D, Hammoudi N, Kawase Y, Santos-Gallego CG, Fish K, Levine RA, Hajjar RJ. Ishikawa K, et al. Among authors: aguero j. Am J Physiol Heart Circ Physiol. 2015 Feb 15;308(4):H365-6. doi: 10.1152/ajpheart.00855.2014. Am J Physiol Heart Circ Physiol. 2015. PMID: 25684739 Free article. No abstract available.
Intratracheal Gene Delivery of SERCA2a Ameliorates Chronic Post-Capillary Pulmonary Hypertension: A Large Animal Model.
Aguero J, Ishikawa K, Hadri L, Santos-Gallego CG, Fish KM, Kohlbrenner E, Hammoudi N, Kho C, Lee A, Ibáñez B, García-Alvarez A, Zsebo K, Maron BA, Plataki M, Fuster V, Leopold JA, Hajjar RJ. Aguero J, et al. J Am Coll Cardiol. 2016 May 3;67(17):2032-46. doi: 10.1016/j.jacc.2016.02.049. J Am Coll Cardiol. 2016. PMID: 27126531 Free PMC article.
228 results