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Increased stiffness is the major early abnormality in a pig model of severe aortic stenosis and predisposes to congestive heart failure in the absence of systolic dysfunction.
Ishikawa K, Aguero J, Oh JG, Hammoudi N, Fish LA, Leonardson L, Picatoste B, Santos-Gallego CG, Fish KM, Hajjar RJ. Ishikawa K, et al. Among authors: oh jg. J Am Heart Assoc. 2015 May 20;4(5):e001925. doi: 10.1161/JAHA.115.001925. J Am Heart Assoc. 2015. PMID: 25994443 Free PMC article.
PICOT is a critical regulator of cardiac hypertrophy and cardiomyocyte contractility.
Cha H, Kim JM, Oh JG, Jeong MH, Park CS, Park J, Jeong HJ, Park BK, Lee YH, Jeong D, Yang DK, Bernecker OY, Kim DH, Hajjar RJ, Park WJ. Cha H, et al. Among authors: oh jg. J Mol Cell Cardiol. 2008 Dec;45(6):796-803. doi: 10.1016/j.yjmcc.2008.09.124. Epub 2008 Sep 27. J Mol Cell Cardiol. 2008. PMID: 18929570 Free PMC article.
SUMO1-dependent modulation of SERCA2a in heart failure.
Kho C, Lee A, Jeong D, Oh JG, Chaanine AH, Kizana E, Park WJ, Hajjar RJ. Kho C, et al. Among authors: oh jg. Nature. 2011 Sep 7;477(7366):601-5. doi: 10.1038/nature10407. Nature. 2011. PMID: 21900893 Free PMC article.
The role of SUMO-1 in cardiac oxidative stress and hypertrophy.
Lee A, Jeong D, Mitsuyama S, Oh JG, Liang L, Ikeda Y, Sadoshima J, Hajjar RJ, Kho C. Lee A, et al. Among authors: oh jg. Antioxid Redox Signal. 2014 Nov 10;21(14):1986-2001. doi: 10.1089/ars.2014.5983. Epub 2014 Aug 4. Antioxid Redox Signal. 2014. PMID: 24893265 Free PMC article.
Matricellular Protein CCN5 Reverses Established Cardiac Fibrosis.
Jeong D, Lee MA, Li Y, Yang DK, Kho C, Oh JG, Hong G, Lee A, Song MH, LaRocca TJ, Chen J, Liang L, Mitsuyama S, D'Escamard V, Kovacic JC, Kwak TH, Hajjar RJ, Park WJ. Jeong D, et al. Among authors: oh jg. J Am Coll Cardiol. 2016 Apr 5;67(13):1556-1568. doi: 10.1016/j.jacc.2016.01.030. J Am Coll Cardiol. 2016. PMID: 27150688 Free PMC article.
84 results