Ellerby LM - Search Results

1

Integration-independent Transgenic Huntington Disease Fragment Mouse Models Reveal Distinct Phenotypes and Life Span in Vivo.

O'Brien R, DeGiacomo F, Holcomb J, Bonner A, Ring KL, Zhang N, Zafar K, Weiss A, Lager B, Schilling B, Gibson BW, Chen S, Kwak S, Ellerby LM. O'Brien R, et al. Among authors: ellerby lm. J Biol Chem. 2015 Jul 31;290(31):19287-306. doi: 10.1074/jbc.M114.623561. Epub 2015 May 29. J Biol Chem. 2015. PMID: 26025364 Free PMC article.

2

A ketogenic diet reduces age-induced chronic neuroinflammation in mice Running title: ketogenic diet and brain inflammaging.

Nomura M, Murad NF, Madhavan SS, Eap B, Garcia TY, Aguirre CG, Verdin E, Ellerby L, Furman D, Newman JC. Nomura M, et al. bioRxiv [Preprint]. 2023 Dec 4:2023.12.01.569598. doi: 10.1101/2023.12.01.569598. bioRxiv. 2023. Update in: Aging Biol. 2024;2:20240038. doi: 10.59368/agingbio.20240038 PMID: 38106160 Free PMC article. Updated. Preprint.

3

Double-stranded RNA-dependent protein kinase, PKR, binds preferentially to Huntington's disease (HD) transcripts and is activated in HD tissue.

Peel AL, Rao RV, Cottrell BA, Hayden MR, Ellerby LM, Bredesen DE. Peel AL, et al. Among authors: ellerby lm. Hum Mol Genet. 2001 Jul 15;10(15):1531-8. doi: 10.1093/hmg/10.15.1531. Hum Mol Genet. 2001. PMID: 11468270

4

Hunting for excitement: NMDA receptors in Huntington's disease.

Ellerby LM. Ellerby LM. Neuron. 2002 Mar 14;33(6):841-2. doi: 10.1016/s0896-6273(02)00631-1. Neuron. 2002. PMID: 11906690 Free article.

5

Calpain activation in Huntington's disease.

Gafni J, Ellerby LM. Gafni J, et al. Among authors: ellerby lm. J Neurosci. 2002 Jun 15;22(12):4842-9. doi: 10.1523/JNEUROSCI.22-12-04842.2002. J Neurosci. 2002. PMID: 12077181 Free PMC article.

6

An artificially designed pore-forming protein with anti-tumor effects.

Ellerby HM, Lee S, Ellerby LM, Chen S, Kiyota T, del Rio G, Sugihara G, Sun Y, Bredesen DE, Arap W, Pasqualini R. Ellerby HM, et al. Among authors: ellerby lm. J Biol Chem. 2003 Sep 12;278(37):35311-6. doi: 10.1074/jbc.M300474200. Epub 2003 May 14. J Biol Chem. 2003. PMID: 12750379 Free article.

7

Kennedy's disease. Phosphorylation of the polyglutamine-expanded form of androgen receptor regulates its cleavage by caspase-3 and enhances cell death.

LaFevre-Bernt MA, Ellerby LM. LaFevre-Bernt MA, et al. Among authors: ellerby lm. J Biol Chem. 2003 Sep 12;278(37):34918-24. doi: 10.1074/jbc.M302841200. Epub 2003 Jun 24. J Biol Chem. 2003. PMID: 12824190 Free article.

8

Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease.

Hermel E, Gafni J, Propp SS, Leavitt BR, Wellington CL, Young JE, Hackam AS, Logvinova AV, Peel AL, Chen SF, Hook V, Singaraja R, Krajewski S, Goldsmith PC, Ellerby HM, Hayden MR, Bredesen DE, Ellerby LM. Hermel E, et al. Among authors: ellerby lm, ellerby hm. Cell Death Differ. 2004 Apr;11(4):424-38. doi: 10.1038/sj.cdd.4401358. Cell Death Differ. 2004. PMID: 14713958

9

Inhibition of calpain cleavage of huntingtin reduces toxicity: accumulation of calpain/caspase fragments in the nucleus.

Gafni J, Hermel E, Young JE, Wellington CL, Hayden MR, Ellerby LM. Gafni J, et al. Among authors: ellerby lm. J Biol Chem. 2004 May 7;279(19):20211-20. doi: 10.1074/jbc.M401267200. Epub 2004 Feb 23. J Biol Chem. 2004. PMID: 14981075 Free article.

10

FGF-2 promotes neurogenesis and neuroprotection and prolongs survival in a transgenic mouse model of Huntington's disease.

Jin K, LaFevre-Bernt M, Sun Y, Chen S, Gafni J, Crippen D, Logvinova A, Ross CA, Greenberg DA, Ellerby LM. Jin K, et al. Among authors: ellerby lm. Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):18189-94. doi: 10.1073/pnas.0506375102. Epub 2005 Dec 2. Proc Natl Acad Sci U S A. 2005. PMID: 16326808 Free PMC article.

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