Perez-Pinera P - Search Results

1

Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators.

Polstein LR, Perez-Pinera P, Kocak DD, Vockley CM, Bledsoe P, Song L, Safi A, Crawford GE, Reddy TE, Gersbach CA. Polstein LR, et al. Genome Res. 2015 Aug;25(8):1158-69. doi: 10.1101/gr.179044.114. Epub 2015 May 29. Genome Res. 2015. PMID: 26025803 Free PMC article.

2

Advances in targeted genome editing.

Perez-Pinera P, Ousterout DG, Gersbach CA. Perez-Pinera P, et al. Curr Opin Chem Biol. 2012 Aug;16(3-4):268-77. doi: 10.1016/j.cbpa.2012.06.007. Epub 2012 Jul 20. Curr Opin Chem Biol. 2012. PMID: 22819644 Free PMC article. Review.

3

RNA-guided gene activation by CRISPR-Cas9-based transcription factors.

Perez-Pinera P, Kocak DD, Vockley CM, Adler AF, Kabadi AM, Polstein LR, Thakore PI, Glass KA, Ousterout DG, Leong KW, Guilak F, Crawford GE, Reddy TE, Gersbach CA. Perez-Pinera P, et al. Nat Methods. 2013 Oct;10(10):973-6. doi: 10.1038/nmeth.2600. Epub 2013 Jul 25. Nat Methods. 2013. PMID: 23892895 Free PMC article.

4

Activating human genes with zinc finger proteins, transcription activator-like effectors and CRISPR/Cas9 for gene therapy and regenerative medicine.

Gersbach CA, Perez-Pinera P. Gersbach CA, et al. Expert Opin Ther Targets. 2014 Aug;18(8):835-9. doi: 10.1517/14728222.2014.913572. Epub 2014 Jun 11. Expert Opin Ther Targets. 2014. PMID: 24917359 Free PMC article.

5

Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases.

Perez-Pinera P, Ousterout DG, Brown MT, Gersbach CA. Perez-Pinera P, et al. Nucleic Acids Res. 2012 Apr;40(8):3741-52. doi: 10.1093/nar/gkr1214. Epub 2011 Dec 14. Nucleic Acids Res. 2012. PMID: 22169954 Free PMC article.

6

Synergistic and tunable human gene activation by combinations of synthetic transcription factors.

Perez-Pinera P, Ousterout DG, Brunger JM, Farin AM, Glass KA, Guilak F, Crawford GE, Hartemink AJ, Gersbach CA. Perez-Pinera P, et al. Nat Methods. 2013 Mar;10(3):239-42. doi: 10.1038/nmeth.2361. Epub 2013 Feb 3. Nat Methods. 2013. PMID: 23377379 Free PMC article.

7

Mammalian Synthetic Biology: Engineering Biological Systems.

Black JB, Perez-Pinera P, Gersbach CA. Black JB, et al. Annu Rev Biomed Eng. 2017 Jun 21;19:249-277. doi: 10.1146/annurev-bioeng-071516-044649. Annu Rev Biomed Eng. 2017. PMID: 28633563 Review.

8

Reading frame correction by targeted genome editing restores dystrophin expression in cells from Duchenne muscular dystrophy patients.

Ousterout DG, Perez-Pinera P, Thakore PI, Kabadi AM, Brown MT, Qin X, Fedrigo O, Mouly V, Tremblay JP, Gersbach CA. Ousterout DG, et al. Mol Ther. 2013 Sep;21(9):1718-26. doi: 10.1038/mt.2013.111. Epub 2013 Jun 4. Mol Ther. 2013. PMID: 23732986 Free PMC article.

9

Correction of dystrophin expression in cells from Duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases.

Ousterout DG, Kabadi AM, Thakore PI, Perez-Pinera P, Brown MT, Majoros WH, Reddy TE, Gersbach CA. Ousterout DG, et al. Mol Ther. 2015 Mar;23(3):523-32. doi: 10.1038/mt.2014.234. Epub 2014 Dec 10. Mol Ther. 2015. PMID: 25492562 Free PMC article.

10

Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage.

Brunger JM, Huynh NP, Guenther CM, Perez-Pinera P, Moutos FT, Sanchez-Adams J, Gersbach CA, Guilak F. Brunger JM, et al. Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):E798-806. doi: 10.1073/pnas.1321744111. Epub 2014 Feb 18. Proc Natl Acad Sci U S A. 2014. PMID: 24550481 Free PMC article.

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