Friedman LJ - Search Results

1

Multi-wavelength single-molecule fluorescence analysis of transcription mechanisms.

Friedman LJ, Gelles J. Friedman LJ, et al. Methods. 2015 Sep 15;86:27-36. doi: 10.1016/j.ymeth.2015.05.026. Epub 2015 May 30. Methods. 2015. PMID: 26032816 Free PMC article.

2

Viewing dynamic assembly of molecular complexes by multi-wavelength single-molecule fluorescence.

Friedman LJ, Chung J, Gelles J. Friedman LJ, et al. Biophys J. 2006 Aug 1;91(3):1023-31. doi: 10.1529/biophysj.106.084004. Epub 2006 May 12. Biophys J. 2006. PMID: 16698779 Free PMC article.

3

Visualizing the splicing of single pre-mRNA molecules in whole cell extract.

Crawford DJ, Hoskins AA, Friedman LJ, Gelles J, Moore MJ. Crawford DJ, et al. Among authors: friedman lj. RNA. 2008 Jan;14(1):170-9. doi: 10.1261/rna.794808. Epub 2007 Nov 19. RNA. 2008. PMID: 18025254 Free PMC article.

4

Ordered and dynamic assembly of single spliceosomes.

Hoskins AA, Friedman LJ, Gallagher SS, Crawford DJ, Anderson EG, Wombacher R, Ramirez N, Cornish VW, Gelles J, Moore MJ. Hoskins AA, et al. Among authors: friedman lj. Science. 2011 Mar 11;331(6022):1289-95. doi: 10.1126/science.1198830. Science. 2011. PMID: 21393538 Free PMC article.

5

Mechanism of transcriptional repression at a bacterial promoter by analysis of single molecules.

Sanchez A, Osborne ML, Friedman LJ, Kondev J, Gelles J. Sanchez A, et al. Among authors: friedman lj. EMBO J. 2011 Aug 9;30(19):3940-6. doi: 10.1038/emboj.2011.273. EMBO J. 2011. PMID: 21829165 Free PMC article.

6

Mechanism of transcription initiation at an activator-dependent promoter defined by single-molecule observation.

Friedman LJ, Gelles J. Friedman LJ, et al. Cell. 2012 Feb 17;148(4):679-89. doi: 10.1016/j.cell.2012.01.018. Cell. 2012. PMID: 22341441 Free PMC article.

7

Single-molecule colocalization FRET evidence that spliceosome activation precedes stable approach of 5' splice site and branch site.

Crawford DJ, Hoskins AA, Friedman LJ, Gelles J, Moore MJ. Crawford DJ, et al. Among authors: friedman lj. Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):6783-8. doi: 10.1073/pnas.1219305110. Epub 2013 Apr 8. Proc Natl Acad Sci U S A. 2013. PMID: 23569281 Free PMC article.

8

RNA polymerase approaches its promoter without long-range sliding along DNA.

Friedman LJ, Mumm JP, Gelles J. Friedman LJ, et al. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9740-5. doi: 10.1073/pnas.1300221110. Epub 2013 May 29. Proc Natl Acad Sci U S A. 2013. PMID: 23720315 Free PMC article.

9

Alternative spliceosome assembly pathways revealed by single-molecule fluorescence microscopy.

Shcherbakova I, Hoskins AA, Friedman LJ, Serebrov V, Corrêa IR Jr, Xu MQ, Gelles J, Moore MJ. Shcherbakova I, et al. Among authors: friedman lj. Cell Rep. 2013 Oct 17;5(1):151-65. doi: 10.1016/j.celrep.2013.08.026. Epub 2013 Sep 26. Cell Rep. 2013. PMID: 24075986 Free PMC article.

10

The covalent trimethoprim chemical tag facilitates single molecule imaging with organic fluorophores.

Wang TY, Friedman LJ, Gelles J, Min W, Hoskins AA, Cornish VW. Wang TY, et al. Among authors: friedman lj. Biophys J. 2014 Jan 7;106(1):272-8. doi: 10.1016/j.bpj.2013.11.4488. Biophys J. 2014. PMID: 24411259 Free PMC article.

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