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Leishmania infantum trypanothione reductase is a promiscuous enzyme carrying an NADPH:O2 oxidoreductase activity shared by glutathione reductase.
Biochim Biophys Acta. 2015 Sep;1850(9):1891-7. doi: 10.1016/j.bbagen.2015.05.022. Epub 2015 May 29.
Biochim Biophys Acta. 2015.
PMID: 26033467
Inhibition of Leishmania infantum trypanothione reductase by azole-based compounds: a comparative analysis with its physiological substrate by X-ray crystallography.
Baiocco P, Poce G, Alfonso S, Cocozza M, Porretta GC, Colotti G, Biava M, Moraca F, Botta M, Yardley V, Fiorillo A, Lantella A, Malatesta F, Ilari A.
Baiocco P, et al. Among authors: lantella a.
ChemMedChem. 2013 Jul;8(7):1175-83. doi: 10.1002/cmdc.201300176. Epub 2013 Jun 3.
ChemMedChem. 2013.
PMID: 23733388
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Effect of single amino acid substitution observed in cancer on Pim-1 kinase thermodynamic stability and structure.
Lori C, Lantella A, Pasquo A, Alexander LT, Knapp S, Chiaraluce R, Consalvi V.
Lori C, et al. Among authors: lantella a.
PLoS One. 2013 Jun 5;8(6):e64824. doi: 10.1371/journal.pone.0064824. Print 2013.
PLoS One. 2013.
PMID: 23755147
Free PMC article.
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