Irwin SM - Search Results

1

Presence of multiple lesion types with vastly different microenvironments in C3HeB/FeJ mice following aerosol infection with Mycobacterium tuberculosis.

Irwin SM, Driver E, Lyon E, Schrupp C, Ryan G, Gonzalez-Juarrero M, Basaraba RJ, Nuermberger EL, Lenaerts AJ. Irwin SM, et al. Dis Model Mech. 2015 Jun;8(6):591-602. doi: 10.1242/dmm.019570. Epub 2015 Mar 30. Dis Model Mech. 2015. PMID: 26035867 Free PMC article.

2

Evaluation of a mouse model of necrotic granuloma formation using C3HeB/FeJ mice for testing of drugs against Mycobacterium tuberculosis.

Driver ER, Ryan GJ, Hoff DR, Irwin SM, Basaraba RJ, Kramnik I, Lenaerts AJ. Driver ER, et al. Among authors: irwin sm. Antimicrob Agents Chemother. 2012 Jun;56(6):3181-95. doi: 10.1128/AAC.00217-12. Epub 2012 Apr 2. Antimicrob Agents Chemother. 2012. PMID: 22470120 Free PMC article.

3

Evaluation of moxifloxacin-containing regimens in pathologically distinct murine tuberculosis models.

Li SY, Irwin SM, Converse PJ, Mdluli KE, Lenaerts AJ, Nuermberger EL. Li SY, et al. Among authors: irwin sm. Antimicrob Agents Chemother. 2015 Jul;59(7):4026-30. doi: 10.1128/AAC.00105-15. Epub 2015 Apr 27. Antimicrob Agents Chemother. 2015. PMID: 25918146 Free PMC article.

4

Bedaquiline and Pyrazinamide Treatment Responses Are Affected by Pulmonary Lesion Heterogeneity in Mycobacterium tuberculosis Infected C3HeB/FeJ Mice.

Irwin SM, Prideaux B, Lyon ER, Zimmerman MD, Brooks EJ, Schrupp CA, Chen C, Reichlen MJ, Asay BC, Voskuil MI, Nuermberger EL, Andries K, Lyons MA, Dartois V, Lenaerts AJ. Irwin SM, et al. ACS Infect Dis. 2016 Apr 8;2(4):251-267. doi: 10.1021/acsinfecdis.5b00127. Epub 2016 Feb 24. ACS Infect Dis. 2016. PMID: 27227164 Free PMC article.

5

Limited activity of clofazimine as a single drug in a mouse model of tuberculosis exhibiting caseous necrotic granulomas.

Irwin SM, Gruppo V, Brooks E, Gilliland J, Scherman M, Reichlen MJ, Leistikow R, Kramnik I, Nuermberger EL, Voskuil MI, Lenaerts AJ. Irwin SM, et al. Antimicrob Agents Chemother. 2014 Jul;58(7):4026-34. doi: 10.1128/AAC.02565-14. Epub 2014 May 5. Antimicrob Agents Chemother. 2014. PMID: 24798275 Free PMC article.

6

Memory T lymphocytes generated by Mycobacterium bovis BCG vaccination reside within a CD4 CD44lo CD62 ligand(hi) population.

Kipnis A, Irwin S, Izzo AA, Basaraba RJ, Orme IM. Kipnis A, et al. Infect Immun. 2005 Nov;73(11):7759-64. doi: 10.1128/IAI.73.11.7759-7764.2005. Infect Immun. 2005. PMID: 16239580 Free PMC article.

7

Host-Mediated Bioactivation of Pyrazinamide: Implications for Efficacy, Resistance, and Therapeutic Alternatives.

Via LE, Savic R, Weiner DM, Zimmerman MD, Prideaux B, Irwin SM, Lyon E, O'Brien P, Gopal P, Eum S, Lee M, Lanoix JP, Dutta NK, Shim T, Cho JS, Kim W, Karakousis PC, Lenaerts A, Nuermberger E, Barry CE 3rd, Dartois V. Via LE, et al. Among authors: irwin sm. ACS Infect Dis. 2015 May 8;1(5):203-214. doi: 10.1021/id500028m. ACS Infect Dis. 2015. PMID: 26086040 Free PMC article.

8

Phenotypic definition of effector and memory T-lymphocyte subsets in mice chronically infected with Mycobacterium tuberculosis.

Henao-Tamayo MI, Ordway DJ, Irwin SM, Shang S, Shanley C, Orme IM. Henao-Tamayo MI, et al. Among authors: irwin sm. Clin Vaccine Immunol. 2010 Apr;17(4):618-25. doi: 10.1128/CVI.00368-09. Epub 2010 Jan 27. Clin Vaccine Immunol. 2010. PMID: 20107011 Free PMC article.

9

Immune response induced by three Mycobacterium bovis BCG substrains with diverse regions of deletion in a C57BL/6 mouse model.

Irwin SM, Goodyear A, Keyser A, Christensen R, Troudt JM, Taylor JL, Bohsali A, Briken V, Izzo AA. Irwin SM, et al. Clin Vaccine Immunol. 2008 May;15(5):750-6. doi: 10.1128/CVI.00018-08. Epub 2008 Mar 19. Clin Vaccine Immunol. 2008. PMID: 18353924 Free PMC article.

10

T lymphocyte surface expression of exhaustion markers as biomarkers of the efficacy of chemotherapy for tuberculosis.

Henao-Tamayo M, Irwin SM, Shang S, Ordway D, Orme IM. Henao-Tamayo M, et al. Among authors: irwin sm. Tuberculosis (Edinb). 2011 Jul;91(4):308-13. doi: 10.1016/j.tube.2011.04.001. Epub 2011 Apr 29. Tuberculosis (Edinb). 2011. PMID: 21530406 Free PMC article.

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