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Page 1
Synthesis and structure-activity relationship of aminoarylthiazole derivatives as correctors of the chloride transport defect in cystic fibrosis.
Pesce E, Bellotti M, Liessi N, Guariento S, Damonte G, Cichero E, Galatini A, Salis A, Gianotti A, Pedemonte N, Zegarra-Moran O, Fossa P, Galietta LJ, Millo E. Pesce E, et al. Among authors: gianotti a. Eur J Med Chem. 2015 Jun 24;99:14-35. doi: 10.1016/j.ejmech.2015.05.030. Epub 2015 May 28. Eur J Med Chem. 2015. PMID: 26041577
Identification, Structure-Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indoles as a Novel Class of CFTR Potentiators.
Brindani N, Gianotti A, Giovani S, Giacomina F, Di Fruscia P, Sorana F, Bertozzi SM, Ottonello G, Goldoni L, Penna I, Russo D, Summa M, Bertorelli R, Ferrera L, Pesce E, Sondo E, Galietta LJV, Bandiera T, Pedemonte N, Bertozzi F. Brindani N, et al. Among authors: gianotti a. J Med Chem. 2020 Oct 8;63(19):11169-11194. doi: 10.1021/acs.jmedchem.0c01050. Epub 2020 Sep 18. J Med Chem. 2020. PMID: 32946228 Free PMC article.
Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia.
Scudieri P, Caci E, Bruno S, Ferrera L, Schiavon M, Sondo E, Tomati V, Gianotti A, Zegarra-Moran O, Pedemonte N, Rea F, Ravazzolo R, Galietta LJ. Scudieri P, et al. Among authors: gianotti a. J Physiol. 2012 Dec 1;590(23):6141-55. doi: 10.1113/jphysiol.2012.240838. Epub 2012 Sep 17. J Physiol. 2012. PMID: 22988141 Free PMC article.
Discovery of a picomolar potency pharmacological corrector of the mutant CFTR chloride channel.
Pedemonte N, Bertozzi F, Caci E, Sorana F, Di Fruscia P, Tomati V, Ferrera L, Rodríguez-Gimeno A, Berti F, Pesce E, Sondo E, Gianotti A, Scudieri P, Bandiera T, Galietta LJV. Pedemonte N, et al. Among authors: gianotti a. Sci Adv. 2020 Feb 21;6(8):eaay9669. doi: 10.1126/sciadv.aay9669. eCollection 2020 Feb. Sci Adv. 2020. PMID: 32128418 Free PMC article.
108 results