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African Swine Fever Virus Georgia 2007 with a Deletion of Virulence-Associated Gene 9GL (B119L), when Administered at Low Doses, Leads to Virus Attenuation in Swine and Induces an Effective Protection against Homologous Challenge.
O'Donnell V, Holinka LG, Krug PW, Gladue DP, Carlson J, Sanford B, Alfano M, Kramer E, Lu Z, Arzt J, Reese B, Carrillo C, Risatti GR, Borca MV. O'Donnell V, et al. Among authors: arzt j. J Virol. 2015 Aug;89(16):8556-66. doi: 10.1128/JVI.00969-15. Epub 2015 Jun 10. J Virol. 2015. PMID: 26063424 Free PMC article.
Interaction of foot-and-mouth disease virus nonstructural protein 3A with host protein DCTN3 is important for viral virulence in cattle.
Gladue DP, O'Donnell V, Baker-Bransetter R, Pacheco JM, Holinka LG, Arzt J, Pauszek S, Fernandez-Sainz I, Fletcher P, Brocchi E, Lu Z, Rodriguez LL, Borca MV. Gladue DP, et al. Among authors: arzt j. J Virol. 2014 Mar;88(5):2737-47. doi: 10.1128/JVI.03059-13. Epub 2013 Dec 18. J Virol. 2014. PMID: 24352458 Free PMC article.
The progressive adaptation of a georgian isolate of African swine fever virus to vero cells leads to a gradual attenuation of virulence in swine corresponding to major modifications of the viral genome.
Krug PW, Holinka LG, O'Donnell V, Reese B, Sanford B, Fernandez-Sainz I, Gladue DP, Arzt J, Rodriguez L, Risatti GR, Borca MV. Krug PW, et al. Among authors: arzt j. J Virol. 2015 Feb;89(4):2324-32. doi: 10.1128/JVI.03250-14. Epub 2014 Dec 10. J Virol. 2015. PMID: 25505073 Free PMC article.
137 results