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Synthesis and Biological Validation of a Harmine-Based, Central Nervous System (CNS)-Avoidant, Selective, Human β-Cell Regenerative Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase A (DYRK1A) Inhibitor.
Kumar K, Wang P, Wilson J, Zlatanic V, Berrouet C, Khamrui S, Secor C, Swartz EA, Lazarus M, Sanchez R, Stewart AF, Garcia-Ocana A, DeVita RJ. Kumar K, et al. Among authors: devita rj. J Med Chem. 2020 Mar 26;63(6):2986-3003. doi: 10.1021/acs.jmedchem.9b01379. Epub 2020 Feb 19. J Med Chem. 2020. PMID: 32003560 Free PMC article.
Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential.
Wu K, Huynh KQ, Lu I, Moustakim M, Miao H, Yu C, Haeusgen MJ, Hopkins BD, Huang L, Zheng N, Sanchez R, DeVita RJ, Pan ZQ. Wu K, et al. Among authors: devita rj. Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):e2007328118. doi: 10.1073/pnas.2007328118. Proc Natl Acad Sci U S A. 2021. PMID: 33602808 Free PMC article.
Dissecting the Contributions of Cooperating Gene Mutations to Cancer Phenotypes and Drug Responses with Patient-Derived iPSCs.
Chang CJ, Kotini AG, Olszewska M, Georgomanoli M, Teruya-Feldstein J, Sperber H, Sanchez R, DeVita R, Martins TJ, Abdel-Wahab O, Bradley RK, Papapetrou EP. Chang CJ, et al. Stem Cell Reports. 2018 May 8;10(5):1610-1624. doi: 10.1016/j.stemcr.2018.03.020. Epub 2018 Apr 19. Stem Cell Reports. 2018. PMID: 29681544 Free PMC article.
75 results