Shalek AK - Search Results

1

Marrying microfluidics and microwells for parallel, high-throughput single-cell genomics.

Wadsworth MH 2nd, Hughes TK, Shalek AK. Wadsworth MH 2nd, et al. Among authors: shalek ak. Genome Biol. 2015 Jun 20;16(1):129. doi: 10.1186/s13059-015-0695-0. Genome Biol. 2015. PMID: 26087845 Free PMC article.

2

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma.

Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suvà ML, Regev A, Bernstein BE. Patel AP, et al. Among authors: shalek ak. Science. 2014 Jun 20;344(6190):1396-401. doi: 10.1126/science.1254257. Epub 2014 Jun 12. Science. 2014. PMID: 24925914 Free PMC article.

3

Preparation of Single-Cell RNA-Seq Libraries for Next Generation Sequencing.

Trombetta JJ, Gennert D, Lu D, Satija R, Shalek AK, Regev A. Trombetta JJ, et al. Among authors: shalek ak. Curr Protoc Mol Biol. 2014 Jul 1;107:4.22.1-4.22.17. doi: 10.1002/0471142727.mb0422s107. Curr Protoc Mol Biol. 2014. PMID: 24984854 Free PMC article. Review.

4

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets.

Macosko EZ, Basu A, Satija R, Nemesh J, Shekhar K, Goldman M, Tirosh I, Bialas AR, Kamitaki N, Martersteck EM, Trombetta JJ, Weitz DA, Sanes JR, Shalek AK, Regev A, McCarroll SA. Macosko EZ, et al. Among authors: shalek ak. Cell. 2015 May 21;161(5):1202-1214. doi: 10.1016/j.cell.2015.05.002. Cell. 2015. PMID: 26000488 Free PMC article.

5

MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data.

Finak G, McDavid A, Yajima M, Deng J, Gersuk V, Shalek AK, Slichter CK, Miller HW, McElrath MJ, Prlic M, Linsley PS, Gottardo R. Finak G, et al. Among authors: shalek ak. Genome Biol. 2015 Dec 10;16:278. doi: 10.1186/s13059-015-0844-5. Genome Biol. 2015. PMID: 26653891 Free PMC article.

6

A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages.

Kimmerling RJ, Lee Szeto G, Li JW, Genshaft AS, Kazer SW, Payer KR, de Riba Borrajo J, Blainey PC, Irvine DJ, Shalek AK, Manalis SR. Kimmerling RJ, et al. Among authors: shalek ak. Nat Commun. 2016 Jan 6;7:10220. doi: 10.1038/ncomms10220. Nat Commun. 2016. PMID: 26732280 Free PMC article.

7

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq.

Tirosh I, Izar B, Prakadan SM, Wadsworth MH 2nd, Treacy D, Trombetta JJ, Rotem A, Rodman C, Lian C, Murphy G, Fallahi-Sichani M, Dutton-Regester K, Lin JR, Cohen O, Shah P, Lu D, Genshaft AS, Hughes TK, Ziegler CG, Kazer SW, Gaillard A, Kolb KE, Villani AC, Johannessen CM, Andreev AY, Van Allen EM, Bertagnolli M, Sorger PK, Sullivan RJ, Flaherty KT, Frederick DT, Jané-Valbuena J, Yoon CH, Rozenblatt-Rosen O, Shalek AK, Regev A, Garraway LA. Tirosh I, et al. Among authors: shalek ak. Science. 2016 Apr 8;352(6282):189-96. doi: 10.1126/science.aad0501. Science. 2016. PMID: 27124452 Free PMC article.

8

Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction.

Genshaft AS, Li S, Gallant CJ, Darmanis S, Prakadan SM, Ziegler CG, Lundberg M, Fredriksson S, Hong J, Regev A, Livak KJ, Landegren U, Shalek AK. Genshaft AS, et al. Among authors: shalek ak. Genome Biol. 2016 Sep 19;17(1):188. doi: 10.1186/s13059-016-1045-6. Genome Biol. 2016. PMID: 27640647 Free PMC article.

9

Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput.

Gierahn TM, Wadsworth MH 2nd, Hughes TK, Bryson BD, Butler A, Satija R, Fortune S, Love JC, Shalek AK. Gierahn TM, et al. Among authors: shalek ak. Nat Methods. 2017 Apr;14(4):395-398. doi: 10.1038/nmeth.4179. Epub 2017 Feb 13. Nat Methods. 2017. PMID: 28192419 Free PMC article.

10

Single-cell analyses to tailor treatments.

Shalek AK, Benson M. Shalek AK, et al. Sci Transl Med. 2017 Sep 20;9(408):eaan4730. doi: 10.1126/scitranslmed.aan4730. Sci Transl Med. 2017. PMID: 28931656 Free PMC article. Review.

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