Kaiser RJ - Search Results

1

Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells.

Hendel A, Bak RO, Clark JT, Kennedy AB, Ryan DE, Roy S, Steinfeld I, Lunstad BD, Kaiser RJ, Wilkens AB, Bacchetta R, Tsalenko A, Dellinger D, Bruhn L, Porteus MH. Hendel A, et al. Among authors: kaiser rj. Nat Biotechnol. 2015 Sep;33(9):985-989. doi: 10.1038/nbt.3290. Epub 2015 Jun 29. Nat Biotechnol. 2015. PMID: 26121415 Free PMC article.

2

Phosphonoacetate Modifications Enhance the Stability and Editing Yields of Guide RNAs for Cas9 Editors.

Ryan DE, Diamant-Levi T, Steinfeld I, Taussig D, Visal-Shah S, Thakker S, Lunstad BD, Kaiser RJ, McCaffrey R, Ortiz M, Townsend J, Welch WRW, Singh M, Curry B, Dellinger DJ, Bruhn L. Ryan DE, et al. Among authors: kaiser rj. Biochemistry. 2023 Dec 19;62(24):3512-3520. doi: 10.1021/acs.biochem.1c00768. Epub 2022 Apr 18. Biochemistry. 2023. PMID: 35436085 Free PMC article.

3

The Degradation of dG Phosphoramidites in Solution.

Hargreaves JS, Kaiser R, Wolber PK. Hargreaves JS, et al. Nucleosides Nucleotides Nucleic Acids. 2015;34(10):691-707. doi: 10.1080/15257770.2015.1071846. Epub 2015 Sep 23. Nucleosides Nucleotides Nucleic Acids. 2015. PMID: 26397361

4

The human mitochondrial tRNAMet: structure/function relationship of a unique modification in the decoding of unconventional codons.

Bilbille Y, Gustilo EM, Harris KA, Jones CN, Lusic H, Kaiser RJ, Delaney MO, Spremulli LL, Deiters A, Agris PF. Bilbille Y, et al. Among authors: kaiser rj. J Mol Biol. 2011 Feb 18;406(2):257-74. doi: 10.1016/j.jmb.2010.11.042. Epub 2010 Dec 17. J Mol Biol. 2011. PMID: 21168417 Free PMC article.

5

Preparation of 5'-silyl-2'-orthoester ribonucleosides for use in oligoribonucleotide synthesis.

Scaringe SA, Kitchen D, Kaiser RJ, Marshall WS. Scaringe SA, et al. Among authors: kaiser rj. Curr Protoc Nucleic Acid Chem. 2004 May;Chapter 2:Unit 2.10. doi: 10.1002/0471142700.nc0210s16. Curr Protoc Nucleic Acid Chem. 2004. PMID: 18428924 Review.

6

Chromophoric 5'-O-Silyl protection of N-protected 2'-ACE ribonucleosides for solid-phase RNA synthesis.

Delaney MO, Thomas A, Ricketts C, Kitchen DE, Kaiser RJ. Delaney MO, et al. Among authors: kaiser rj. Curr Protoc Nucleic Acid Chem. 2008 Mar;Chapter 2:Unit 2.14. doi: 10.1002/0471142700.nc0214s32. Curr Protoc Nucleic Acid Chem. 2008. PMID: 18428803

7

Recent advances in the high-speed solid phase synthesis of RNA.

Marshall WS, Kaiser RJ. Marshall WS, et al. Among authors: kaiser rj. Curr Opin Chem Biol. 2004 Jun;8(3):222-9. doi: 10.1016/j.cbpa.2004.04.012. Curr Opin Chem Biol. 2004. PMID: 15183319 Review.

8

Salicylhydroxamic acid functionalized affinity membranes for specific immobilization of proteins and oligonucleotides.

Springer AL, Gall AS, Hughes KA, Kaiser RJ, Li G, Lund KP. Springer AL, et al. Among authors: kaiser rj. J Biomol Tech. 2003 Sep;14(3):183-90. J Biomol Tech. 2003. PMID: 13678148 Free PMC article.

9

A rapid method for manual or automated purification of fluorescently labeled nucleic acids for sequencing, genotyping, and microarrays.

Springer AL, Booth LR, Braid MD, Houde CM, Hughes KA, Kaiser RJ, Pedrak C, Spicer DA, Stolyar S. Springer AL, et al. Among authors: kaiser rj. J Biomol Tech. 2003 Mar;14(1):17-32. J Biomol Tech. 2003. PMID: 12901608 Free PMC article.

10

Phenylboronic acid-salicylhydroxamic acid bioconjugates. 2. Polyvalent immobilization of protein ligands for affinity chromatography.

Wiley JP, Hughes KA, Kaiser RJ, Kesicki EA, Lund KP, Stolowitz ML. Wiley JP, et al. Among authors: kaiser rj. Bioconjug Chem. 2001 Mar-Apr;12(2):240-50. doi: 10.1021/bc000086l. Bioconjug Chem. 2001. PMID: 11312685

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