Ooi JS - Search Results

1

DENGUE VIRUS. Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers.

Fibriansah G, Ibarra KD, Ng TS, Smith SA, Tan JL, Lim XN, Ooi JS, Kostyuchenko VA, Wang J, de Silva AM, Harris E, Crowe JE Jr, Lok SM. Fibriansah G, et al. Among authors: ooi js. Science. 2015 Jul 3;349(6243):88-91. doi: 10.1126/science.aaa8651. Science. 2015. PMID: 26138979 Free PMC article.

2

Structure of the thermally stable Zika virus.

Kostyuchenko VA, Lim EX, Zhang S, Fibriansah G, Ng TS, Ooi JS, Shi J, Lok SM. Kostyuchenko VA, et al. Among authors: ooi js. Nature. 2016 May 19;533(7603):425-8. doi: 10.1038/nature17994. Epub 2016 Apr 19. Nature. 2016. PMID: 27093288

3

Neutralization mechanism of a highly potent antibody against Zika virus.

Zhang S, Kostyuchenko VA, Ng TS, Lim XN, Ooi JSG, Lambert S, Tan TY, Widman DG, Shi J, Baric RS, Lok SM. Zhang S, et al. Nat Commun. 2016 Nov 24;7:13679. doi: 10.1038/ncomms13679. Nat Commun. 2016. PMID: 27882950 Free PMC article.

4

Molecular basis of dengue virus serotype 2 morphological switch from 29°C to 37°C.

Lim XN, Shan C, Marzinek JK, Dong H, Ng TS, Ooi JSG, Fibriansah G, Wang J, Verma CS, Bond PJ, Shi PY, Lok SM. Lim XN, et al. PLoS Pathog. 2019 Sep 19;15(9):e1007996. doi: 10.1371/journal.ppat.1007996. eCollection 2019 Sep. PLoS Pathog. 2019. PMID: 31536610 Free PMC article.

5

How NS1 Antibodies Prevent Severe Flavivirus Disease.

Ooi JSG, Lok SM. Ooi JSG, et al. Trends Biochem Sci. 2021 Jul;46(7):519-521. doi: 10.1016/j.tibs.2021.03.005. Epub 2021 Apr 22. Trends Biochem Sci. 2021. PMID: 33895084

6

CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever.

Shu B, Ooi JSG, Tan AWK, Ng TS, Dejnirattisai W, Mongkolsapaya J, Fibriansah G, Shi J, Kostyuchenko VA, Screaton GR, Lok SM. Shu B, et al. Among authors: ooi jsg. Nat Commun. 2022 Nov 9;13(1):6756. doi: 10.1038/s41467-022-34415-1. Nat Commun. 2022. PMID: 36347841 Free PMC article.

7

A prM mutation that attenuates dengue virus replication in human cells enhances midgut infection in mosquitoes.

Choi ANX, Siriphanitchakorn T, Choy MM, Ooi JSG, Manuel M, Tan HC, Lin LZ, Yap X, Gubler DJ, Ooi EE. Choi ANX, et al. Among authors: ooi jsg. Sci Transl Med. 2024 Jul 31;16(758):eadk4769. doi: 10.1126/scitranslmed.adk4769. Epub 2024 Jul 31. Sci Transl Med. 2024. PMID: 39083584

8

Dengue virus-elicited tryptase induces endothelial permeability and shock.

Rathore AP, Mantri CK, Aman SA, Syenina A, Ooi J, Jagaraj CJ, Goh CC, Tissera H, Wilder-Smith A, Ng LG, Gubler DJ, St John AL. Rathore AP, et al. J Clin Invest. 2019 Jul 2;129(10):4180-4193. doi: 10.1172/JCI128426. J Clin Invest. 2019. PMID: 31265436 Free PMC article.

9

RNase2 is a possible trigger of acute-on-chronic inflammation leading to mRNA vaccine-associated cardiac complication.

Ong EZ, Koh CWT, Tng DJH, Ooi JSG, Yee JX, Chew VSY, Leong YS, Gunasegaran K, Yeo CP, Oon LLE, Sim JXY, Chan KR, Low JG, Ooi EE. Ong EZ, et al. Among authors: ooi jsg. Med. 2023 Jun 9;4(6):353-360.e2. doi: 10.1016/j.medj.2023.04.001. Epub 2023 Apr 26. Med. 2023. PMID: 37105176 Free PMC article.

10

Immune gene expression analysis indicates the potential of a self-amplifying Covid-19 mRNA vaccine.

Ong EZ, Yee JX, Ooi JSG, Syenina A, de Alwis R, Chen S, Sim JXY, Kalimuddin S, Leong YS, Chan YFZ, Sekulovich R, Sullivan BM, Lindert K, Sullivan SB, Chivukula P, Hughes SG, Low JG, Ooi EE, Chan KR. Ong EZ, et al. Among authors: ooi jsg. NPJ Vaccines. 2022 Nov 28;7(1):154. doi: 10.1038/s41541-022-00573-y. NPJ Vaccines. 2022. PMID: 36443317 Free PMC article.

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