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Safety Observations With 3 Years of Denosumab Exposure: Comparison Between Subjects Who Received Denosumab During the Randomized FREEDOM Trial and Subjects Who Crossed Over to Denosumab During the FREEDOM Extension.
Watts NB, Brown JP, Papapoulos S, Lewiecki EM, Kendler DL, Dakin P, Wagman RB, Wang A, Daizadeh NS, Smith S, Bone HG. Watts NB, et al. Among authors: wang a. J Bone Miner Res. 2017 Jul;32(7):1481-1485. doi: 10.1002/jbmr.3119. Epub 2017 Apr 3. J Bone Miner Res. 2017. PMID: 28277603 Free article. Clinical Trial.
Further reductions in nonvertebral fracture rate with long-term denosumab treatment in the FREEDOM open-label extension and influence of hip bone mineral density after 3 years.
Ferrari S, Adachi JD, Lippuner K, Zapalowski C, Miller PD, Reginster JY, Törring O, Kendler DL, Daizadeh NS, Wang A, O'Malley CD, Wagman RB, Libanati C, Lewiecki EM. Ferrari S, et al. Among authors: wang a. Osteoporos Int. 2015 Dec;26(12):2763-71. doi: 10.1007/s00198-015-3179-x. Epub 2015 Jun 12. Osteoporos Int. 2015. PMID: 26068295 Free PMC article. Clinical Trial.
The effect of 8 or 5 years of denosumab treatment in postmenopausal women with osteoporosis: results from the FREEDOM Extension study.
Papapoulos S, Lippuner K, Roux C, Lin CJ, Kendler DL, Lewiecki EM, Brandi ML, Czerwiński E, Franek E, Lakatos P, Mautalen C, Minisola S, Reginster JY, Jensen S, Daizadeh NS, Wang A, Gavin M, Libanati C, Wagman RB, Bone HG. Papapoulos S, et al. Among authors: wang a. Osteoporos Int. 2015 Dec;26(12):2773-83. doi: 10.1007/s00198-015-3234-7. Epub 2015 Jul 23. Osteoporos Int. 2015. PMID: 26202488 Free PMC article. Clinical Trial.
Observations following discontinuation of long-term denosumab therapy.
McClung MR, Wagman RB, Miller PD, Wang A, Lewiecki EM. McClung MR, et al. Among authors: wang a. Osteoporos Int. 2017 May;28(5):1723-1732. doi: 10.1007/s00198-017-3919-1. Epub 2017 Jan 31. Osteoporos Int. 2017. PMID: 28144701 Free PMC article. Clinical Trial.
Effect of denosumab on trabecular bone score in postmenopausal women with osteoporosis.
McClung MR, Lippuner K, Brandi ML, Zanchetta JR, Bone HG, Chapurlat R, Hans D, Wang A, Zapalowski C, Libanati C. McClung MR, et al. Among authors: wang a. Osteoporos Int. 2017 Oct;28(10):2967-2973. doi: 10.1007/s00198-017-4140-y. Epub 2017 Jul 26. Osteoporos Int. 2017. PMID: 28748386 Free article. Clinical Trial.
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