Slusher BS - Search Results

1

High Affinity Dopamine D3 Receptor (D3R)-Selective Antagonists Attenuate Heroin Self-Administration in Wild-Type but not D3R Knockout Mice.

Boateng CA, Bakare OM, Zhan J, Banala AK, Burzynski C, Pommier E, Keck TM, Donthamsetti P, Javitch JA, Rais R, Slusher BS, Xi ZX, Newman AH. Boateng CA, et al. Among authors: slusher bs. J Med Chem. 2015 Aug 13;58(15):6195-213. doi: 10.1021/acs.jmedchem.5b00776. Epub 2015 Jul 23. J Med Chem. 2015. PMID: 26203768 Free PMC article.

2

Design and pharmacological activity of phosphinic acid based NAALADase inhibitors.

Jackson PF, Tays KL, Maclin KM, Ko YS, Li W, Vitharana D, Tsukamoto T, Stoermer D, Lu XC, Wozniak K, Slusher BS. Jackson PF, et al. Among authors: slusher bs. J Med Chem. 2001 Nov 22;44(24):4170-5. doi: 10.1021/jm0001774. J Med Chem. 2001. PMID: 11708918

3

Synthesis and biological evaluation of thiol-based inhibitors of glutamate carboxypeptidase II: discovery of an orally active GCP II inhibitor.

Majer P, Jackson PF, Delahanty G, Grella BS, Ko YS, Li W, Liu Q, Maclin KM, Poláková J, Shaffer KA, Stoermer D, Vitharana D, Wang EY, Zakrzewski A, Rojas C, Slusher BS, Wozniak KM, Burak E, Limsakun T, Tsukamoto T. Majer P, et al. Among authors: slusher bs. J Med Chem. 2003 May 8;46(10):1989-96. doi: 10.1021/jm020515w. J Med Chem. 2003. PMID: 12723961

4

Structure-activity relationship of trihexyphenidyl analogs with respect to the dopamine transporter in the on going search for a cocaine inhibitor.

Dar DE, Thiruvazhi M, Abraham P, Kitayama S, Kopajtic TA, Gamliel A, Slusher BS, Carroll FI, Uhl GR. Dar DE, et al. Among authors: slusher bs. Eur J Med Chem. 2005 Oct;40(10):1013-21. doi: 10.1016/j.ejmech.2005.04.016. Epub 2005 Jul 11. Eur J Med Chem. 2005. PMID: 16009468

5

Structural optimization of thiol-based inhibitors of glutamate carboxypeptidase II by modification of the P1' side chain.

Majer P, Hin B, Stoermer D, Adams J, Xu W, Duvall BR, Delahanty G, Liu Q, Stathis MJ, Wozniak KM, Slusher BS, Tsukamoto T. Majer P, et al. Among authors: slusher bs. J Med Chem. 2006 May 18;49(10):2876-85. doi: 10.1021/jm051019l. J Med Chem. 2006. PMID: 16686531

6

Oral administration of the NAALADase inhibitor GPI-5693 attenuates cocaine-induced reinstatement of drug-seeking behavior in rats.

Peng XQ, Li J, Gardner EL, Ashby CR Jr, Thomas A, Wozniak K, Slusher BS, Xi ZX. Peng XQ, et al. Among authors: slusher bs. Eur J Pharmacol. 2010 Feb 10;627(1-3):156-61. doi: 10.1016/j.ejphar.2009.10.062. Epub 2009 Oct 31. Eur J Pharmacol. 2010. PMID: 19887067 Free PMC article.

7

Inhibition of NAALADase by 2-PMPA attenuates cocaine-induced relapse in rats: a NAAG-mGluR2/3-mediated mechanism.

Xi ZX, Li X, Peng XQ, Li J, Chun L, Gardner EL, Thomas AG, Slusher BS, Ashby CR Jr. Xi ZX, et al. Among authors: slusher bs. J Neurochem. 2010 Jan;112(2):564-76. doi: 10.1111/j.1471-4159.2009.06478.x. Epub 2009 Nov 6. J Neurochem. 2010. PMID: 19895667 Free PMC article.

8

The role of glutamate signaling in pain processes and its regulation by GCP II inhibition.

Wozniak KM, Rojas C, Wu Y, Slusher BS. Wozniak KM, et al. Among authors: slusher bs. Curr Med Chem. 2012;19(9):1323-34. doi: 10.2174/092986712799462630. Curr Med Chem. 2012. PMID: 22304711 Review.

9

Glutamate in CNS neurodegeneration and cognition and its regulation by GCPII inhibition.

Rahn KA, Slusher BS, Kaplin AI. Rahn KA, et al. Among authors: slusher bs. Curr Med Chem. 2012;19(9):1335-45. doi: 10.2174/092986712799462649. Curr Med Chem. 2012. PMID: 22304712 Review.

10

Design, synthesis, and pharmacological evaluation of glutamate carboxypeptidase II (GCPII) inhibitors based on thioalkylbenzoic acid scaffolds.

Stoermer D, Vitharana D, Hin N, Delahanty G, Duvall B, Ferraris DV, Grella BS, Hoover R, Rojas C, Shanholtz MK, Smith KP, Stathis M, Wu Y, Wozniak KM, Slusher BS, Tsukamoto T. Stoermer D, et al. Among authors: slusher bs. J Med Chem. 2012 Jun 28;55(12):5922-32. doi: 10.1021/jm300488m. Epub 2012 Jun 12. J Med Chem. 2012. PMID: 22642259

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