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Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells.
Patsch C, Challet-Meylan L, Thoma EC, Urich E, Heckel T, O'Sullivan JF, Grainger SJ, Kapp FG, Sun L, Christensen K, Xia Y, Florido MH, He W, Pan W, Prummer M, Warren CR, Jakob-Roetne R, Certa U, Jagasia R, Freskgård PO, Adatto I, Kling D, Huang P, Zon LI, Chaikof EL, Gerszten RE, Graf M, Iacone R, Cowan CA. Patsch C, et al. Among authors: freskgard po. Nat Cell Biol. 2015 Aug;17(8):994-1003. doi: 10.1038/ncb3205. Epub 2015 Jul 27. Nat Cell Biol. 2015. PMID: 26214132 Free PMC article.
Cargo Delivery into the Brain by in vivo identified Transport Peptides.
Urich E, Schmucki R, Ruderisch N, Kitas E, Certa U, Jacobsen H, Schweitzer C, Bergadano A, Ebeling M, Loetscher H, Freskgård PO. Urich E, et al. Among authors: freskgard po. Sci Rep. 2015 Sep 28;5:14104. doi: 10.1038/srep14104. Sci Rep. 2015. PMID: 26411801 Free PMC article.
Antibody therapies in CNS diseases.
Freskgård PO, Urich E. Freskgård PO, et al. Neuropharmacology. 2017 Jul 1;120:38-55. doi: 10.1016/j.neuropharm.2016.03.014. Epub 2016 Mar 10. Neuropharmacology. 2017. PMID: 26972827 Review.
Brain Shuttle Neprilysin reduces central Amyloid-β levels.
Campos CR, Kemble AM, Niewoehner J, Freskgård PO, Urich E. Campos CR, et al. Among authors: freskgard po. PLoS One. 2020 Mar 10;15(3):e0229850. doi: 10.1371/journal.pone.0229850. eCollection 2020. PLoS One. 2020. PMID: 32155191 Free PMC article.
Potent and Selective BACE-1 Peptide Inhibitors Lower Brain Aβ Levels Mediated by Brain Shuttle Transport.
Ruderisch N, Schlatter D, Kuglstatter A, Guba W, Huber S, Cusulin C, Benz J, Rufer AC, Hoernschemeyer J, Schweitzer C, Bülau T, Gärtner A, Hoffmann E, Niewoehner J, Patsch C, Baumann K, Loetscher H, Kitas E, Freskgård PO. Ruderisch N, et al. Among authors: freskgard po. EBioMedicine. 2017 Oct;24:76-92. doi: 10.1016/j.ebiom.2017.09.004. Epub 2017 Sep 7. EBioMedicine. 2017. PMID: 28923680 Free PMC article.
Targeting neuronal lysosomal dysfunction caused by β-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct.
Gehrlein A, Udayar V, Anastasi N, Morella ML, Ruf I, Brugger D, von der Mark S, Thoma R, Rufer A, Heer D, Pfahler N, Jochner A, Niewoehner J, Wolf L, Fueth M, Ebeling M, Villaseñor R, Zhu Y, Deen MC, Shan X, Ehsaei Z, Taylor V, Sidransky E, Vocadlo DJ, Freskgård PO, Jagasia R. Gehrlein A, et al. Among authors: freskgard po. Nat Commun. 2023 Apr 12;14(1):2057. doi: 10.1038/s41467-023-37632-4. Nat Commun. 2023. PMID: 37045813 Free PMC article.
47 results