Goate A - Search Results

1

A multiancestry study identifies novel genetic associations with CHRNA5 methylation in human brain and risk of nicotine dependence.

Hancock DB, Wang JC, Gaddis NC, Levy JL, Saccone NL, Stitzel JA, Goate A, Bierut LJ, Johnson EO. Hancock DB, et al. Among authors: goate a. Hum Mol Genet. 2015 Oct 15;24(20):5940-54. doi: 10.1093/hmg/ddv303. Epub 2015 Jul 28. Hum Mol Genet. 2015. PMID: 26220977 Free PMC article.

2

Use of a predictive model derived from in vivo endophenotype measurements to demonstrate associations with a complex locus, CYP2A6.

Bloom AJ, Harari O, Martinez M, Madden PA, Martin NG, Montgomery GW, Rice JP, Murphy SE, Bierut LJ, Goate A. Bloom AJ, et al. Among authors: goate a. Hum Mol Genet. 2012 Jul 1;21(13):3050-62. doi: 10.1093/hmg/dds114. Epub 2012 Mar 26. Hum Mol Genet. 2012. PMID: 22451501 Free PMC article.

3

A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.

Kapoor M, Wang JC, Wetherill L, Le N, Bertelsen S, Hinrichs AL, Budde J, Agrawal A, Bucholz K, Dick D, Harari O, Hesselbrock V, Kramer J, Nurnberger JI Jr, Rice J, Saccone N, Schuckit M, Tischfield J, Porjesz B, Edenberg HJ, Bierut L, Foroud T, Goate A. Kapoor M, et al. Among authors: goate a. Hum Genet. 2013 Oct;132(10):1141-51. doi: 10.1007/s00439-013-1318-z. Epub 2013 Jun 7. Hum Genet. 2013. PMID: 23743675 Free PMC article.

4

Variants in two adjacent genes, EGLN2 and CYP2A6, influence smoking behavior related to disease risk via different mechanisms.

Bloom AJ, Baker TB, Chen LS, Breslau N, Hatsukami D, Bierut LJ, Goate A. Bloom AJ, et al. Among authors: goate a. Hum Mol Genet. 2014 Jan 15;23(2):555-61. doi: 10.1093/hmg/ddt432. Epub 2013 Sep 17. Hum Mol Genet. 2014. PMID: 24045616 Free PMC article.

5

Rare missense variants in CHRNB3 and CHRNA3 are associated with risk of alcohol and cocaine dependence.

Haller G, Kapoor M, Budde J, Xuei X, Edenberg H, Nurnberger J, Kramer J, Brooks A, Tischfield J, Almasy L, Agrawal A, Bucholz K, Rice J, Saccone N, Bierut L, Goate A. Haller G, et al. Among authors: goate a. Hum Mol Genet. 2014 Feb 1;23(3):810-9. doi: 10.1093/hmg/ddt463. Epub 2013 Sep 20. Hum Mol Genet. 2014. PMID: 24057674 Free PMC article.

6

Beyond cigarettes per day. A genome-wide association study of the biomarker carbon monoxide.

Bloom AJ, Hartz SM, Baker TB, Chen LS, Piper ME, Fox L, Martinez M, Hatsukami D, Johnson EO, Laurie CC, Saccone NL, Goate A, Bierut LJ. Bloom AJ, et al. Among authors: goate a. Ann Am Thorac Soc. 2014 Sep;11(7):1003-10. doi: 10.1513/AnnalsATS.201401-010OC. Ann Am Thorac Soc. 2014. PMID: 25072098 Free PMC article. Clinical Trial.

7

Common polymorphisms in FMO1 are associated with nicotine dependence.

Hinrichs AL, Murphy SE, Wang JC, Saccone S, Saccone N, Steinbach JH, Goate A, Stevens VL, Bierut LJ. Hinrichs AL, et al. Among authors: goate a. Pharmacogenet Genomics. 2011 Jul;21(7):397-402. doi: 10.1097/FPC.0b013e328346886f. Pharmacogenet Genomics. 2011. PMID: 21540762 Free PMC article.

8

Effects upon in-vivo nicotine metabolism reveal functional variation in FMO3 associated with cigarette consumption.

Bloom AJ, Murphy SE, Martinez M, von Weymarn LB, Bierut LJ, Goate A. Bloom AJ, et al. Among authors: goate a. Pharmacogenet Genomics. 2013 Feb;23(2):62-8. doi: 10.1097/FPC.0b013e32835c3b48. Pharmacogenet Genomics. 2013. PMID: 23211429 Free PMC article.

9

Dosage transmission disequilibrium test (dTDT) for linkage and association detection.

Zhang Z, Wang JC, Howells W, Lin P, Agrawal A, Edenberg HJ, Tischfield JA, Schuckit MA, Bierut LJ, Goate A, Rice JP. Zhang Z, et al. Among authors: goate a. PLoS One. 2013 May 14;8(5):e63526. doi: 10.1371/journal.pone.0063526. Print 2013. PLoS One. 2013. PMID: 23691058 Free PMC article.

10

Pharmacotherapy effects on smoking cessation vary with nicotine metabolism gene (CYP2A6).

Chen LS, Bloom AJ, Baker TB, Smith SS, Piper ME, Martinez M, Saccone N, Hatsukami D, Goate A, Bierut L. Chen LS, et al. Among authors: goate a. Addiction. 2014 Jan;109(1):128-137. doi: 10.1111/add.12353. Epub 2013 Nov 11. Addiction. 2014. PMID: 24033696 Free PMC article. Clinical Trial.

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