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ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1.
Kijas AW, Lim YC, Bolderson E, Cerosaletti K, Gatei M, Jakob B, Tobias F, Taucher-Scholz G, Gueven N, Oakley G, Concannon P, Wolvetang E, Khanna KK, Wiesmüller L, Lavin MF. Kijas AW, et al. Among authors: lim yc. Nucleic Acids Res. 2015 Sep 30;43(17):8352-67. doi: 10.1093/nar/gkv754. Epub 2015 Aug 3. Nucleic Acids Res. 2015. PMID: 26240375 Free PMC article.
A novel role for hSMG-1 in stress granule formation.
Brown JA, Roberts TL, Richards R, Woods R, Birrell G, Lim YC, Ohno S, Yamashita A, Abraham RT, Gueven N, Lavin MF. Brown JA, et al. Among authors: lim yc. Mol Cell Biol. 2011 Nov;31(22):4417-29. doi: 10.1128/MCB.05987-11. Epub 2011 Sep 12. Mol Cell Biol. 2011. PMID: 21911475 Free PMC article.
EphA3 maintains tumorigenicity and is a therapeutic target in glioblastoma multiforme.
Day BW, Stringer BW, Al-Ejeh F, Ting MJ, Wilson J, Ensbey KS, Jamieson PR, Bruce ZC, Lim YC, Offenhäuser C, Charmsaz S, Cooper LT, Ellacott JK, Harding A, Leveque L, Inglis P, Allan S, Walker DG, Lackmann M, Osborne G, Khanna KK, Reynolds BA, Lickliter JD, Boyd AW. Day BW, et al. Among authors: lim yc. Cancer Cell. 2013 Feb 11;23(2):238-48. doi: 10.1016/j.ccr.2013.01.007. Cancer Cell. 2013. PMID: 23410976 Free article.
AarF Domain Containing Kinase 3 (ADCK3) Mutant Cells Display Signs of Oxidative Stress, Defects in Mitochondrial Homeostasis and Lysosomal Accumulation.
Cullen JK, Abdul Murad N, Yeo A, McKenzie M, Ward M, Chong KL, Schieber NL, Parton RG, Lim YC, Wolvetang E, Maghzal GJ, Stocker R, Lavin MF. Cullen JK, et al. Among authors: lim yc. PLoS One. 2016 Feb 11;11(2):e0148213. doi: 10.1371/journal.pone.0148213. eCollection 2016. PLoS One. 2016. PMID: 26866375 Free PMC article.
Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage.
Quek H, Luff J, Cheung K, Kozlov S, Gatei M, Lee CS, Bellingham MC, Noakes PG, Lim YC, Barnett NL, Dingwall S, Wolvetang E, Mashimo T, Roberts TL, Lavin MF. Quek H, et al. Among authors: lim yc. J Leukoc Biol. 2017 Apr;101(4):927-947. doi: 10.1189/jlb.4VMA0716-316R. Epub 2016 Nov 28. J Leukoc Biol. 2017. PMID: 27895165
A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype.
Quek H, Luff J, Cheung K, Kozlov S, Gatei M, Lee CS, Bellingham MC, Noakes PG, Lim YC, Barnett NL, Dingwall S, Wolvetang E, Mashimo T, Roberts TL, Lavin MF. Quek H, et al. Among authors: lim yc. Hum Mol Genet. 2017 Jan 1;26(1):109-123. doi: 10.1093/hmg/ddw371. Hum Mol Genet. 2017. PMID: 28007901
515 results