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Evidence for fumonisin inhibition of ceramide synthase in humans consuming maize-based foods and living in high exposure communities in Guatemala.
Riley RT, Torres O, Matute J, Gregory SG, Ashley-Koch AE, Showker JL, Mitchell T, Voss KA, Maddox JR, Gelineau-van Waes JB. Riley RT, et al. Among authors: mitchell t. Mol Nutr Food Res. 2015 Nov;59(11):2209-24. doi: 10.1002/mnfr.201500499. Epub 2015 Sep 3. Mol Nutr Food Res. 2015. PMID: 26264677 Free PMC article.
Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals.
Zitomer NC, Mitchell T, Voss KA, Bondy GS, Pruett ST, Garnier-Amblard EC, Liebeskind LS, Park H, Wang E, Sullards MC, Merrill AH Jr, Riley RT. Zitomer NC, et al. Among authors: mitchell t. J Biol Chem. 2009 Feb 20;284(8):4786-95. doi: 10.1074/jbc.M808798200. Epub 2008 Dec 18. J Biol Chem. 2009. PMID: 19095642 Free PMC article.
Response.
Palencia ER, Mitchell TR, Bacon CW. Palencia ER, et al. J Food Prot. 2015 Jan;78(1):8-12. J Food Prot. 2015. PMID: 25581172 No abstract available.
A blood spot method for detecting fumonisin-induced changes in putative sphingolipid biomarkers in LM/Bc mice and humans.
Riley RT, Showker JL, Lee CM, Zipperer CE, Mitchell TR, Voss KA, Zitomer NC, Torres O, Matute J, Gregory SG, Ashley-Koch AE, Maddox JR, Gardner N, Gelineau-Van Waes JB. Riley RT, et al. Among authors: mitchell tr. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2015;32(6):934-49. doi: 10.1080/19440049.2015.1027746. Epub 2015 Apr 10. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2015. PMID: 25833119
Pyrrocidine, a molecular off switch for fumonisin biosynthesis.
Gao M, Glenn AE, Gu X, Mitchell TR, Satterlee T, Duke MV, Scheffler BE, Gold SE. Gao M, et al. Among authors: mitchell tr. PLoS Pathog. 2020 Jul 6;16(7):e1008595. doi: 10.1371/journal.ppat.1008595. eCollection 2020 Jul. PLoS Pathog. 2020. PMID: 32628727 Free PMC article.
2,096 results