Parham LR - Search Results

1

Rash in lapatinib-treated patients is not associated with human leukocyte antigen polymorphisms.

Parham LR, Briley LP, King KS, Byrne J, Rappold E, Goss PE, Spraggs CF. Parham LR, et al. Pharmacogenomics. 2015;16(11):1227-9. doi: 10.2217/pgs.15.69. Epub 2015 Aug 12. Pharmacogenomics. 2015. PMID: 26265235

2

Prospective validation of HLA-DRB1*07:01 allele carriage as a predictive risk factor for lapatinib-induced liver injury.

Schaid DJ, Spraggs CF, McDonnell SK, Parham LR, Cox CJ, Ejlertsen B, Finkelstein DM, Rappold E, Curran J, Cardon LR, Goss PE. Schaid DJ, et al. Among authors: parham lr. J Clin Oncol. 2014 Aug 1;32(22):2296-303. doi: 10.1200/JCO.2013.52.9867. Epub 2014 Mar 31. J Clin Oncol. 2014. PMID: 24687830 Clinical Trial.

3

Comprehensive genome-wide evaluation of lapatinib-induced liver injury yields a single genetic signal centered on known risk allele HLA-DRB1*07:01.

Parham LR, Briley LP, Li L, Shen J, Newcombe PJ, King KS, Slater AJ, Dilthey A, Iqbal Z, McVean G, Cox CJ, Nelson MR, Spraggs CF. Parham LR, et al. Pharmacogenomics J. 2016 Apr;16(2):180-5. doi: 10.1038/tpj.2015.40. Epub 2015 May 19. Pharmacogenomics J. 2016. PMID: 25987243 Free PMC article. Clinical Trial.

4

Characterisation of the HLA-DRB1*07:01 biomarker for lapatinib-induced liver toxicity during treatment of early-stage breast cancer patients with lapatinib in combination with trastuzumab and/or taxanes.

Spraggs CF, Parham LR, Briley LP, Warren L, Williams LS, Fraser DJ, Jiang Z, Aziz Z, Ahmed S, Demetriou G, Mehta A, Jackson N, Byrne J, Andersson M, Toi M, Harris L, Gralow J, Zujewski JA, Crescenzo R, Armour A, Perez E, Piccart M. Spraggs CF, et al. Among authors: parham lr. Pharmacogenomics J. 2018 May 22;18(3):480-486. doi: 10.1038/tpj.2017.39. Epub 2017 Aug 8. Pharmacogenomics J. 2018. PMID: 28786423 Clinical Trial.

5

Lapatinib-induced liver injury characterized by class II HLA and Gilbert's syndrome genotypes.

Spraggs CF, Parham LR, Hunt CM, Dollery CT. Spraggs CF, et al. Among authors: parham lr. Clin Pharmacol Ther. 2012 Apr;91(4):647-52. doi: 10.1038/clpt.2011.277. Epub 2012 Feb 22. Clin Pharmacol Ther. 2012. PMID: 22357454 Clinical Trial.

6

Different effects of the BIM deletion polymorphism on treatment of solid tumors by the tyrosine kinase inhibitors (TKI) pazopanib, sunitinib, and lapatinib.

Spraggs CF, Parham LR, Song K, Briley LP, Johnson T, Russo M, Tada H, du Bois A, Xu CF. Spraggs CF, et al. Among authors: parham lr. Ann Oncol. 2015 Jul;26(7):1515-7. doi: 10.1093/annonc/mdv211. Epub 2015 Apr 28. Ann Oncol. 2015. PMID: 25922065 Free article. No abstract available.

7

Evaluation of the effect of UGT1A1 polymorphisms on the pharmacokinetics of oral and long-acting injectable cabotegravir.

Patel P, Xue Z, King KS, Parham L, Ford S, Lou Y, Bakshi KK, Sutton K, Margolis D, Hughes AR, Spreen WR. Patel P, et al. J Antimicrob Chemother. 2020 Aug 1;75(8):2240-2248. doi: 10.1093/jac/dkaa147. J Antimicrob Chemother. 2020. PMID: 32361755 Free PMC article.

8

Pharmacogenetic investigation of efficacy response to mepolizumab in eosinophilic granulomatosis with polyangiitis.

Condreay LD, Parham LR, Qu XA, Steinfeld J, Wechsler ME, Raby BA, Yancey SW, Ghosh S. Condreay LD, et al. Among authors: parham lr. Rheumatol Int. 2020 Aug;40(8):1301-1307. doi: 10.1007/s00296-020-04523-6. Epub 2020 Feb 3. Rheumatol Int. 2020. PMID: 32009195 Free PMC article. Clinical Trial.

9

A Randomized Phase 2 Study of an Anti-Amyloid β Monoclonal Antibody in Geographic Atrophy Secondary to Age-Related Macular Degeneration.

Rosenfeld PJ, Berger B, Reichel E, Danis RP, Gress A, Ye L, Magee M, Parham LR, McLaughlin MM. Rosenfeld PJ, et al. Among authors: parham lr. Ophthalmol Retina. 2018 Oct;2(10):1028-1040. doi: 10.1016/j.oret.2018.03.001. Epub 2018 Apr 17. Ophthalmol Retina. 2018. PMID: 31047490

10

TNFSF13 insufficiency disrupts human colonic epithelial cell-mediated B cell differentiation.

Ma X, Dawany N, Kondo A, Maurer K, Karakasheva T, Shraim R, Williams PA, Parham LR, Simon LA, Danan CH, Conrad MA, Piccoli DA, Devoto M, Sullivan KE, Kaestner KH, Kelsen JR, Hamilton KE. Ma X, et al. Among authors: parham lr. bioRxiv [Preprint]. 2024 Sep 23:2024.09.23.614260. doi: 10.1101/2024.09.23.614260. bioRxiv. 2024. PMID: 39386555 Free PMC article. Preprint.

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