Saavedra A - Search Results

1

Striatal-enriched protein tyrosine phosphatase modulates nociception: evidence from genetic deletion and pharmacological inhibition.

Azkona G, Saavedra A, Aira Z, Aluja D, Xifró X, Baguley T, Alberch J, Ellman JA, Lombroso PJ, Azkue JJ, Pérez-Navarro E. Azkona G, et al. Among authors: saavedra a. Pain. 2016 Feb;157(2):377-386. doi: 10.1097/j.pain.0000000000000329. Pain. 2016. PMID: 26270590 Free PMC article.

2

Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity.

Saavedra A, Giralt A, Rué L, Xifró X, Xu J, Ortega Z, Lucas JJ, Lombroso PJ, Alberch J, Pérez-Navarro E. Saavedra A, et al. J Neurosci. 2011 Jun 1;31(22):8150-62. doi: 10.1523/JNEUROSCI.3446-10.2011. J Neurosci. 2011. PMID: 21632937 Free PMC article.

3

BDNF Induces Striatal-Enriched Protein Tyrosine Phosphatase 61 Degradation Through the Proteasome.

Saavedra A, Puigdellívol M, Tyebji S, Kurup P, Xu J, Ginés S, Alberch J, Lombroso PJ, Pérez-Navarro E. Saavedra A, et al. Mol Neurobiol. 2016 Aug;53(6):4261-4273. doi: 10.1007/s12035-015-9335-7. Epub 2015 Jul 30. Mol Neurobiol. 2016. PMID: 26223799 Free PMC article.

4

Down-regulation of BDNF in cell and animal models increases striatal-enriched protein tyrosine phosphatase 61 (STEP61 ) levels.

Xu J, Kurup P, Azkona G, Baguley TD, Saavedra A, Nairn AC, Ellman JA, Pérez-Navarro E, Lombroso PJ. Xu J, et al. Among authors: saavedra a. J Neurochem. 2016 Jan;136(2):285-94. doi: 10.1111/jnc.13295. Epub 2015 Sep 17. J Neurochem. 2016. PMID: 26316048 Free PMC article.

5

Age-related changes in STriatal-Enriched protein tyrosine Phosphatase levels: Regulation by BDNF.

Cases S, Saavedra A, Tyebji S, Giralt A, Alberch J, Pérez-Navarro E. Cases S, et al. Among authors: saavedra a. Mol Cell Neurosci. 2018 Jan;86:41-49. doi: 10.1016/j.mcn.2017.11.003. Epub 2017 Nov 6. Mol Cell Neurosci. 2018. PMID: 29122705 Free article.

6

Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: role in excitotoxicity.

Xifró X, Giralt A, Saavedra A, García-Martínez JM, Díaz-Hernández M, Lucas JJ, Alberch J, Pérez-Navarro E. Xifró X, et al. Among authors: saavedra a. Neurobiol Dis. 2009 Dec;36(3):461-9. doi: 10.1016/j.nbd.2009.08.012. Epub 2009 Sep 4. Neurobiol Dis. 2009. PMID: 19733666

7

Increased PKA signaling disrupts recognition memory and spatial memory: role in Huntington's disease.

Giralt A, Saavedra A, Carretón O, Xifró X, Alberch J, Pérez-Navarro E. Giralt A, et al. Among authors: saavedra a. Hum Mol Genet. 2011 Nov 1;20(21):4232-47. doi: 10.1093/hmg/ddr351. Epub 2011 Aug 11. Hum Mol Genet. 2011. PMID: 21835884

8

Increased 90-kDa ribosomal S6 kinase (Rsk) activity is protective against mutant huntingtin toxicity.

Xifró X, Anglada-Huguet M, Rué L, Saavedra A, Pérez-Navarro E, Alberch J. Xifró X, et al. Among authors: saavedra a. Mol Neurodegener. 2011 Oct 31;6:74. doi: 10.1186/1750-1326-6-74. Mol Neurodegener. 2011. PMID: 22041125 Free PMC article.

9

Chelerythrine promotes Ca²⁺-dependent calpain activation in neuronal cells in a PKC-independent manner.

Saavedra A, Fernández-García S, Cases S, Puigdellívol M, Alcalá-Vida R, Martín-Flores N, Alberch J, Ginés S, Malagelada C, Pérez-Navarro E. Saavedra A, et al. Biochim Biophys Acta Gen Subj. 2017 Apr;1861(4):922-935. doi: 10.1016/j.bbagen.2017.01.021. Epub 2017 Jan 24. Biochim Biophys Acta Gen Subj. 2017. PMID: 28130160

10

Proteolytic Degradation of Hippocampal STEP₆₁ in LTP and Learning.

Saavedra A, Ballesteros JJ, Tyebji S, Martínez-Torres S, Blázquez G, López-Hidalgo R, Azkona G, Alberch J, Martín ED, Pérez-Navarro E. Saavedra A, et al. Mol Neurobiol. 2019 Feb;56(2):1475-1487. doi: 10.1007/s12035-018-1170-1. Epub 2018 Jun 12. Mol Neurobiol. 2019. PMID: 29948948

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