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Unique Toll-Like Receptor 4 Activation by NAMPT/PBEF Induces NFκB Signaling and Inflammatory Lung Injury.
Camp SM, Ceco E, Evenoski CL, Danilov SM, Zhou T, Chiang ET, Moreno-Vinasco L, Mapes B, Zhao J, Gursoy G, Brown ME, Adyshev DM, Siddiqui SS, Quijada H, Sammani S, Letsiou E, Saadat L, Yousef M, Wang T, Liang J, Garcia JG. Camp SM, et al. Among authors: saadat l. Sci Rep. 2015 Aug 14;5:13135. doi: 10.1038/srep13135. Sci Rep. 2015. PMID: 26272519 Free PMC article.
Nicotinamide phosphoribosyltransferase inhibitor is a novel therapeutic candidate in murine models of inflammatory lung injury.
Moreno-Vinasco L, Quijada H, Sammani S, Siegler J, Letsiou E, Deaton R, Saadat L, Zaidi RS, Messana J, Gann PH, Machado RF, Ma W, Camp SM, Wang T, Garcia JG. Moreno-Vinasco L, et al. Among authors: saadat l. Am J Respir Cell Mol Biol. 2014 Aug;51(2):223-8. doi: 10.1165/rcmb.2012-0519OC. Am J Respir Cell Mol Biol. 2014. PMID: 24588101 Free PMC article.
The NAMPT promoter is regulated by mechanical stress, signal transducer and activator of transcription 5, and acute respiratory distress syndrome-associated genetic variants.
Sun X, Elangovan VR, Mapes B, Camp SM, Sammani S, Saadat L, Ceco E, Ma SF, Flores C, MacDougall MS, Quijada H, Liu B, Kempf CL, Wang T, Chiang ET, Garcia JG. Sun X, et al. Among authors: saadat l. Am J Respir Cell Mol Biol. 2014 Nov;51(5):660-7. doi: 10.1165/rcmb.2014-0117OC. Am J Respir Cell Mol Biol. 2014. PMID: 24821571 Free PMC article.
Phenotypic characterization of murine models of cerebral cavernous malformations.
Zeineddine HA, Girard R, Saadat L, Shen L, Lightle R, Moore T, Cao Y, Hobson N, Shenkar R, Avner K, Chaudager K, Koskimäki J, Polster SP, Fam MD, Shi C, Lopez-Ramirez MA, Tang AT, Gallione C, Kahn ML, Ginsberg M, Marchuk DA, Awad IA. Zeineddine HA, et al. Among authors: saadat l. Lab Invest. 2019 Mar;99(3):319-330. doi: 10.1038/s41374-018-0030-y. Epub 2018 Jun 26. Lab Invest. 2019. PMID: 29946133 Free PMC article.
Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice.
Lopez-Ramirez MA, Pham A, Girard R, Wyseure T, Hale P, Yamashita A, Koskimäki J, Polster S, Saadat L, Romero IA, Esmon CT, Lagarrigue F, Awad IA, Mosnier LO, Ginsberg MH. Lopez-Ramirez MA, et al. Among authors: saadat l. Blood. 2019 Jan 17;133(3):193-204. doi: 10.1182/blood-2018-06-856062. Epub 2018 Nov 15. Blood. 2019. PMID: 30442679 Free PMC article.
54 results