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Site-specific synthesis and characterization of oligonucleotides containing an N6-(2-deoxy-D-erythro-pentofuranosyl)-2,6-diamino-3,4-dihydro-4-oxo-5-N-methylformamidopyrimidine lesion, the ring-opened product from N7-methylation of deoxyguanosine.
Christov PP, Brown KL, Kozekov ID, Stone MP, Harris TM, Rizzo CJ. Christov PP, et al. Chem Res Toxicol. 2008 Dec;21(12):2324-33. doi: 10.1021/tx800352a. Chem Res Toxicol. 2008. PMID: 19053322 Free PMC article.
The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo.
Liu M, Bandaru V, Bond JP, Jaruga P, Zhao X, Christov PP, Burrows CJ, Rizzo CJ, Dizdaroglu M, Wallace SS. Liu M, et al. Among authors: christov pp. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):4925-30. doi: 10.1073/pnas.0908307107. Epub 2010 Feb 25. Proc Natl Acad Sci U S A. 2010. PMID: 20185759 Free PMC article.
The C8-2'-deoxyguanosine adduct of 2-amino-3-methylimidazo[1,2-d]naphthalene, a carbocyclic analogue of the potent mutagen 2-amino-3-methylimidazo[4,5-f]quinoline, is a block to replication in vitro.
Christov PP, Chowdhury G, Garmendia CA, Wang F, Stover JS, Elmquist CE, Kozekova A, Angel KC, Turesky RJ, Stone MP, Guengerich FP, Rizzo CJ. Christov PP, et al. Chem Res Toxicol. 2010 Jun 21;23(6):1076-88. doi: 10.1021/tx100053n. Chem Res Toxicol. 2010. PMID: 20377178 Free PMC article.
46 results