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Page 1
In vivo genome editing of the albumin locus as a platform for protein replacement therapy.
Sharma R, Anguela XM, Doyon Y, Wechsler T, DeKelver RC, Sproul S, Paschon DE, Miller JC, Davidson RJ, Shivak D, Zhou S, Rieders J, Gregory PD, Holmes MC, Rebar EJ, High KA. Sharma R, et al. Among authors: gregory pd. Blood. 2015 Oct 8;126(15):1777-84. doi: 10.1182/blood-2014-12-615492. Epub 2015 Aug 21. Blood. 2015. PMID: 26297739 Free PMC article.
Genome editing with engineered zinc finger nucleases.
Urnov FD, Rebar EJ, Holmes MC, Zhang HS, Gregory PD. Urnov FD, et al. Among authors: gregory pd. Nat Rev Genet. 2010 Sep;11(9):636-46. doi: 10.1038/nrg2842. Nat Rev Genet. 2010. PMID: 20717154 Review.
In vivo genome editing restores haemostasis in a mouse model of haemophilia.
Li H, Haurigot V, Doyon Y, Li T, Wong SY, Bhagwat AS, Malani N, Anguela XM, Sharma R, Ivanciu L, Murphy SL, Finn JD, Khazi FR, Zhou S, Paschon DE, Rebar EJ, Bushman FD, Gregory PD, Holmes MC, High KA. Li H, et al. Among authors: gregory pd. Nature. 2011 Jun 26;475(7355):217-21. doi: 10.1038/nature10177. Nature. 2011. PMID: 21706032 Free PMC article.
Robust ZFN-mediated genome editing in adult hemophilic mice.
Anguela XM, Sharma R, Doyon Y, Miller JC, Li H, Haurigot V, Rohde ME, Wong SY, Davidson RJ, Zhou S, Gregory PD, Holmes MC, High KA. Anguela XM, et al. Among authors: gregory pd. Blood. 2013 Nov 7;122(19):3283-7. doi: 10.1182/blood-2013-04-497354. Epub 2013 Oct 1. Blood. 2013. PMID: 24085764 Free PMC article.
Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells.
Hoban MD, Cost GJ, Mendel MC, Romero Z, Kaufman ML, Joglekar AV, Ho M, Lumaquin D, Gray D, Lill GR, Cooper AR, Urbinati F, Senadheera S, Zhu A, Liu PQ, Paschon DE, Zhang L, Rebar EJ, Wilber A, Wang X, Gregory PD, Holmes MC, Reik A, Hollis RP, Kohn DB. Hoban MD, et al. Among authors: gregory pd. Blood. 2015 Apr 23;125(17):2597-604. doi: 10.1182/blood-2014-12-615948. Epub 2015 Mar 2. Blood. 2015. PMID: 25733580 Free PMC article.
An improved zinc-finger nuclease architecture for highly specific genome editing.
Miller JC, Holmes MC, Wang J, Guschin DY, Lee YL, Rupniewski I, Beausejour CM, Waite AJ, Wang NS, Kim KA, Gregory PD, Pabo CO, Rebar EJ. Miller JC, et al. Among authors: gregory pd. Nat Biotechnol. 2007 Jul;25(7):778-85. doi: 10.1038/nbt1319. Epub 2007 Jul 1. Nat Biotechnol. 2007. PMID: 17603475
135 results